| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4156315 | F | Cytotoxicity against rat C6 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 10 | ALA4152328 | cell-based format | Scientific Literature | |
| 2. | ALA4156316 | F | Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 10 | ALA4152328 | cell-based format | Scientific Literature | |
| 3. | ALA4156317 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Mus musculus | 10 | ALA4152328 | cell-based format | Scientific Literature | |
| 4. | ALA4156318 | T | Selectivity index, ratio of IC50 for mouse NIH/3T3 cells to IC50 for rat C6 cells | 9 | ALA4152328 | assay format | Scientific Literature | ||
| 5. | ALA4156319 | T | Selectivity index, ratio of IC50 for mouse NIH/3T3 cells to IC50 for human A549 cells | 9 | ALA4152328 | assay format | Scientific Literature | ||
| 6. | ALA4156320 | F | Induction of apoptosis in rat C6 cells assessed as early/late apoptotic cells at IC50 after 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 8%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 7. | ALA4156321 | F | Induction of apoptosis in rat C6 cells assessed as viable cells at IC50 after 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 90%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 8. | ALA4156322 | F | Induction of apoptosis in human A549 cells assessed as early/late apoptotic cells at IC50 after 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 7.1%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 9. | ALA4156323 | F | Induction of apoptosis in human A549 cells assessed as viable cells at IC50 after 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 89%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 10. | ALA4156324 | F | Induction of mitochondrial membrane potential loss in rat C6 cells assessed as intact mitochondrial membrane potential at IC50 measured after 24 hrs by JC-1 staining based flow cytometric analysis (Rvb = 80%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 11. | ALA4156325 | F | Induction of mitochondrial membrane potential loss in rat C6 cells at IC50 measured after 24 hrs by JC-1 staining based flow cytometric analysis (Rvb = 19.9%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 12. | ALA4156326 | F | Induction of mitochondrial membrane potential loss in human A549 cells assessed as intact mitochondrial membrane potential at IC50 measured after 24 hrs by JC-1 staining based flow cytometric analysis (Rvb = 90.4%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 13. | ALA4156327 | F | Induction of mitochondrial membrane potential loss in human A549 cells at IC50 measured after 24 hrs by JC-1 staining based flow cytometric analysis (Rvb = 9.8%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 14. | ALA4156328 | F | Induction of apoptosis in rat C6 cells assessed as caspase-3 negative cell level at IC50 after 24 hrs by FITC-A labeled flow cytometry (Rvb = 96.4%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 15. | ALA4156329 | F | Induction of apoptosis in rat C6 cells assessed as caspase-3 positive cell level at IC50 after 24 hrs by FITC-A labeled flow cytometry (Rvb = 4.8%) | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 16. | ALA4156330 | F | Induction of apoptosis in human A549 cells assessed as caspase-3 negative cell level at IC50 after 24 hrs by FITC-A labeled flow cytometry (Rvb = 98.1%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 17. | ALA4156331 | F | Induction of apoptosis in human A549 cells assessed as caspase-3 positive cell level at IC50 after 24 hrs by FITC-A labeled flow cytometry (Rvb = 2.1%) | Homo sapiens | 3 | ALA4152328 | cell-based format | Scientific Literature | |
| 18. | ALA4156332 | B | Inhibition of Akt in rat C6 cells after 24 hrs by ELISA | Rattus norvegicus | 4 | ALA4152328 | cell-based format | Scientific Literature | |
| 19. | ALA4156333 | B | Inhibition of Akt in human A549 cells after 24 hrs by ELISA | Homo sapiens | 4 | ALA4152328 | cell-based format | Scientific Literature | |
| 20. | ALA4156334 | B | Inhibition of FAK phasphorylation at Tyr397 residues in rat C6 cells after 24 hrs by ELISA | Rattus norvegicus | 3 | ALA4152328 | cell-based format | Scientific Literature |
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