| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4150105 | B | Inhibition of NF-kappaB signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced IKKbeta phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4150106 | F | Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as decrease in number of TRAP-positive multinucleated cells after 5 days by microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4150107 | F | Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as decrease in size of TRAP-positive multinucleated cells after 5 days by microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4150108 | F | Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as decrease in TRAP activity at 10 to 40 uM after 5 days by microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4150109 | F | Inhibition of RANKL-induced bone resorption in mouse RAW264.7 cells assessed as reduction in pit formation after 7 days by optical microscopy | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4150110 | A | Cytotoxicity against mouse RANKL-treated RAW264.7 cells assessed as reduction in cell viability at 10 to 40 uM after 72 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4150111 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced NFATc1 mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4150112 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced c-Fos mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4150113 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced TRAP mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4150114 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced MMP-9 mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4150115 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced DC-STAMP mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4150116 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced cathepsin K mRNA level after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4150117 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced NFATc1 protein expression level after 24 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4150118 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced c-Fos protein expression level after 24 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4150119 | B | Inhibition of NF-kappaB/p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced NFATc1 nuclear translocation after 24 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4150120 | B | Inhibition of NF-kappaB signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced Akt phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4150121 | B | Inhibition of NF-kappaB signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced IkappaB phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4150122 | B | Inhibition of p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced p38 phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4150123 | B | Inhibition of p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced JNK phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4150124 | B | Inhibition of p38 MAPK signaling pathway in mouse RAW264.7 cells assessed as reduction in RANKL-induced ERK phosphorylation at 10 to 40 uM after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature |
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