# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4155297 | B | Inhibition of Influenza A virus (A/WSN/1933(H1N1)) wild type neuraminidase using MUNANA as substrate preincubated for 10 mins followed by substrate addition and measured for 15 mins by fluorescence assay | Influenza A virus (A/WSN/1933(H1N1)) | 8 | ALA4152278 | single protein format | Scientific Literature | |
2. | ALA4155298 | B | Inhibition of Influenza A virus (A/WSN/1933(H1N1)) neuraminidase H275Y mutant using MUNANA as substrate preincubated for 10 mins followed by substrate addition and measured for 15 mins by fluorescence assay | Influenza A virus (A/WSN/1933(H1N1)) | 7 | ALA4152278 | single protein format | Scientific Literature | |
3. | ALA4155299 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells expressing wild type neuraminidase assessed as protection against virus-induced cytopathic effect after 48 hrs by CellTiter96 aqueous non-radioactive cell proliferation assay | Influenza A virus | 9 | ALA4152278 | organism-based format | Scientific Literature | |
4. | ALA4155300 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in MDCK cells expressing neuraminidase H275Y mutant assessed as protection against virus-induced cytopathic effect after 48 hrs by CellTiter96 aqueous non-radioactive cell proliferation assay | Influenza A virus | 7 | ALA4152278 | organism-based format | Scientific Literature | |
5. | ALA4155301 | A | Cytotoxicity against MDCK cells after 48 hrs by CellTiter96 aqueous non-radioactive cell proliferation assay | Canis lupus familiaris | 7 | ALA4152278 | cell-based format | Scientific Literature | |
6. | ALA4155302 | P | Half life in HCl/KCl solution at pH 1.3 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4155303 | P | Half life in acetate buffer at pH 4.1 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4155304 | P | Half life in 50 mM phosphate buffer at pH 7.4 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4155305 | P | Half life in 10 mM phosphate buffer at pH 7.4 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4155306 | P | Half life in borate buffer at pH 9.1 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4155307 | P | Half life in glycine buffer at pH 9.2 by HPLC method | 4 | ALA4152278 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4155308 | A | Half life in rat plasma by HPLC method | Rattus norvegicus | 2 | ALA4152278 | cell-free format | Scientific Literature | |
13. | ALA4155316 | F | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) infected in BALB/c mouse assessed as mouse survival rate at 1.2 umol/kg/day administered intranasally for 5 days and measured at day 21 relative to control | Influenza A virus | 2 | ALA4152278 | organism-based format | Scientific Literature |