| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4144310 | F | Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDF1alpha-induced calcium flux pretreated for 25 mins followed by SDF1alpha addition measured for 90 secs by calcium dye-based fluorescence assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 2. | ALA4144311 | A | Antagonist activity at mAChR in human CCRF-CEM cells assessed as inhibition of acetylcholine-stimulated Ca2+ flux pretreated for 25 mins followed by acetylacholine addition measured for 90 secs by calcium dye-based fluorescence assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 3. | ALA4144312 | A | Stability in human liver microsomes assessed as parent compound remaining after 10 mins by LC-MS/MS analysis | Homo sapiens | 28 | microsome format | Scientific Literature | ||
| 4. | ALA4144313 | A | Stability in rat liver microsomes assessed as parent compound remaining after 10 mins by LC-MS/MS analysis | Rattus norvegicus | 28 | microsome format | Scientific Literature | ||
| 5. | ALA4144314 | A | Stability in mouse liver microsomes assessed as parent compound remaining after 10 mins by LC-MS/MS analysis | Mus musculus | 28 | microsome format | Scientific Literature | ||
| 6. | ALA4144315 | A | Permeability of the compound at pH 7.4 by PAMPA | 31 | assay format | Scientific Literature | |||
| 7. | ALA4144316 | A | Permeability of the compound at pH 5.5 by PAMPA | 31 | assay format | Scientific Literature | |||
| 8. | ALA4144317 | A | Inhibition of recombinant human CYP2D6 expressed in insect cell microsomes using AMMC as substrate pretreated for 30 mins followed by NADPH addition measured after 45 mins by fluorescence assay | Homo sapiens | 31 | assay format | Scientific Literature |
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