# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146472 | F | Vasorelaxing activity in Wistar rat endothelium-denuded thoracic aorta ring assessed as reduction in 30 mM KCl-induced contraction after 15 mins | Rattus norvegicus | 68 | ALA4145465 | tissue-based format | Scientific Literature | |
2. | ALA4146473 | F | Vasorelaxing activity in Wistar rat endothelium-denuded thoracic aorta ring assessed as reduction in 30 mM KCl-induced contraction at 300 uM after 15 mins relative to DMSO | Rattus norvegicus | 66 | ALA4145465 | tissue-based format | Scientific Literature | |
3. | ALA4146474 | F | Vasorelaxing activity in Wistar rat endothelium-denuded thoracic aorta ring assessed as reduction in 30 mM KCl-induced contraction after 15 mins in presence of 1 uM glibenclamide | Rattus norvegicus | 5 | ALA4145465 | tissue-based format | Scientific Literature | |
4. | ALA4146475 | F | Vasorelaxing activity in Wistar rat endothelium-denuded thoracic aorta ring assessed as reduction in 30 mM KCl-induced contraction after 15 mins in presence of 10 uM glibenclamide | Rattus norvegicus | 5 | ALA4145465 | tissue-based format | Scientific Literature | |
5. | ALA4146476 | F | Vasorelaxing activity in Wistar rat endothelium-denuded thoracic aorta ring assessed as reduction in 80 mM KCl-induced contraction after 15 mins | Rattus norvegicus | 5 | ALA4145465 | tissue-based format | Scientific Literature | |
6. | ALA4146479 | F | Tracheorelaxant activity in Wistar rat trachea tonus assessed as reduction in 30 mM KCl-induced contraction after 15 mins | Rattus norvegicus | 10 | ALA4145465 | tissue-based format | Scientific Literature | |
7. | ALA4146480 | F | Tracheorelaxant activity in Wistar rat trachea tonus assessed as reduction in 30 mM KCl-induced contraction at 100 uM after 15 mins relative to control | Rattus norvegicus | 10 | ALA4145465 | tissue-based format | Scientific Literature | |
8. | ALA4146481 | F | Ratio of EC50 for Wistar rat trachea tonus to EC50 for Wistar rat endothelium-denuded thoracic aorta ring | Rattus norvegicus | 10 | ALA4145465 | tissue-based format | Scientific Literature | |
9. | ALA4146482 | F | Induction of elastin synthesis in rat VSMC at 50 uM after 48 hrs by ELISA relative to control | Rattus norvegicus | 5 | ALA4145465 | cell-based format | Scientific Literature | |
10. | ALA4146483 | F | Induction of elastin synthesis in rat VSMC at 20 uM after 48 hrs by ELISA | Rattus norvegicus | 5 | ALA4145465 | cell-based format | Scientific Literature | |
11. | ALA4146484 | P | Ionozation constant, pKa of the compound at pH 3 to 12 at 25 degC by UV/VIS spectrophotometric method | 1 | ALA4145465 | small-molecule physicochemical format | Scientific Literature |