| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4156811 | F | Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDF-1alpha-induced calcium release preincubated for 25 mins followed by SDF-1alpha stimulation and measured for 90 secs by calcium flux assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 2. | ALA4156812 | F | Antagonist activity at mAChR in human CCRF-CEM cells assessed as inhibition of acetylcholine-induced calcium release preincubated for 25 mins followed by acetylcholine stimulation and measured for 90 secs by calcium flux assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 3. | ALA4156813 | A | Inhibition of recombinant human CYP2D6 expressed in insect cells microsomes using AMMC as substrate preincubated for 30 mins followed by NADP addition and measured after 45 mins by fluorescence analysis | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 4. | ALA4156814 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 10 mins by LC-MS/MS analysis | Homo sapiens | 34 | microsome format | Scientific Literature | ||
| 5. | ALA4156815 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining after 10 mins by LC-MS/MS analysis | Mus musculus | 29 | microsome format | Scientific Literature | ||
| 6. | ALA4156816 | A | Inhibition of human CYP3A4 | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 7. | ALA4156818 | A | Permeability of compound at pH 7.4 by PAMPA | 31 | assay format | Scientific Literature | |||
| 8. | ALA4156820 | F | Agonist activity at CXCR4 in human CCRF-CEM cells assessed as induction of calcium release incubated for 25 mins by calcium flux assay | Homo sapiens | 33 | cell-based format | Scientific Literature |
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