#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4151257	F	Antidiabetic activity in Goto Kakizaki rats assessed as inhibition of blood glucose AUC at 0.3 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method relative to control	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature
2.	ALA4151258	F	Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assay	Homo sapiens	20	ALA4145665	cell-based format	Scientific Literature
3.	ALA4151259	F	Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins in presence of 100% human serum by HTRF assay	Homo sapiens	20	ALA4145665	cell-based format	Scientific Literature
4.	ALA4151260	F	Antidiabetic activity in Sprague-Dawley rat assessed as inhibition of blood glucose AUC at 3 mg/kg, po treated prior to dextrose challenge and measured after 20 to 60 mins by IPGTT relative to control	Rattus norvegicus	8	ALA4145665	organism-based format	Scientific Literature
5.	ALA4151261	F	Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assay relative to AM-1638	Homo sapiens	20	ALA4145665	cell-based format	Scientific Literature
6.	ALA4151262	F	Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins in presence of 100% human serum by HTRF assay relative to AM-1638	Homo sapiens	20	ALA4145665	cell-based format	Scientific Literature
7.	ALA4151263	F	Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assay	Rattus norvegicus	4	ALA4145665	cell-based format	Scientific Literature
8.	ALA4151264	F	Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assay relative to AM-1638	Rattus norvegicus	4	ALA4145665	cell-based format	Scientific Literature
9.	ALA4151265	F	Antidiabetic activity in po dosed Goto Kakizaki rats assessed as reduction in blood glucose excursion pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
10.	ALA4151266	F	Antidiabetic activity in po dosed Goto Kakizaki rats assessed as plasma concentration required for reduction in blood glucose excursion at MED pretreated for 1 hr followed by dextrose challenge measured 3 hrs post dose by OGTT	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
11.	ALA4151267	A	Fraction unbound in Wistar-Han rat plasma at 1 mg/kg, iv or 2 mg/kg, po administered as single dose	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
12.	ALA4151268	A	Clearance in Wistar-Han rat at 1 mg/kg, iv or 2 mg/kg, po administered as single dose	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
13.	ALA4151269	A	Volume of distribution at steady state in Wistar-Han rat at 1 mg/kg, iv or 2 mg/kg, po administered as single dose	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
14.	ALA4151270	A	Effective half life in Wistar-Han rat at 1 mg/kg, iv or 2 mg/kg, po administered as single dose	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
15.	ALA4151271	A	Oral bioavailability in Wistar-Han rat at 2 mg/kg administered as single dose	Rattus norvegicus	4	ALA4145665	organism-based format	Scientific Literature
16.	ALA4151272	F	Antidiabetic activity in Goto Kakizaki rats assessed as inhibition of blood glucose AUC at 1 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method relative to control	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature
17.	ALA4151273	F	Antidiabetic activity in Goto Kakizaki rats assessed as inhibition of blood glucose AUC at 3 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method relative to control	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature
18.	ALA4151274	F	Antidiabetic activity in Goto Kakizaki rats assessed as inhibition of blood glucose AUC at 10 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method relative to control	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature
19.	ALA4151275	F	Antidiabetic activity in Goto Kakizaki rats assessed as inhibition of blood glucose AUC at 30 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured after 20 to 60 mins by OGTT method relative to control	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature
20.	ALA4151276	F	Antidiabetic activity in Goto Kakizaki rats assessed as plasma concentration required for reduction in blood glucose excursion at 0.3 mg/kg, po pretreated for 1 hr followed by dextrose challenge measured 3 hrs post dose by OGTT	Rattus norvegicus	2	ALA4145665	organism-based format	Scientific Literature