# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146984 | F | In vivo antagonist activity at GnRH receptor in castrated cynomolgus monkey assessed as inhibition of serum luteinizing hormone level at 30 mg/kg, po via gavage administered as single dose measured at 8 hrs post dose by radio-immunoassay relative to basal level | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
2. | ALA4146985 | F | In vivo antagonist activity at GnRH receptor in castrated cynomolgus monkey assessed as inhibition of serum luteinizing hormone level at 30 mg/kg, po via gavage administered as single dose measured at 24 hrs post dose by radio-immunoassay | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
3. | ALA4146986 | A | Cmax in castrated cynomolgus monkey at 30 mg/kg, po via gavage administered as single dose by LC-MS/MS analysis | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
4. | ALA4146987 | A | AUC (0 to infinity) in castrated cynomolgus monkey at 30 mg/kg, po via gavage administered as single dose by LC-MS/MS analysis | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
5. | ALA4146988 | A | Tmax in castrated cynomolgus monkey at 30 mg/kg, po via gavage administered as single dose by LC-MS/MS analysis | Macaca fascicularis | 1 | organism-based format | Scientific Literature |