# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4156727 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by SRB assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
2. | ALA4156728 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4156729 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4156730 | F | Antiproliferative activity against human A375 cells after 48 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4156731 | T | Selectivity ratio of IC50 for human HFF to IC50 for human HCT116 cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA4156732 | T | Selectivity ratio of IC50 for human HFF to IC50 for human HepG2 cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA4156733 | T | Selectivity ratio of IC50 for human HFF to IC50 for human MCF7 cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
8. | ALA4156734 | T | Selectivity ratio of IC50 for human HFF to IC50 for human A375 cells | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA4156735 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G2/M phase at 4.2 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4156736 | F | Induction of apoptosis in human HCT116 cells at 4.2 uM after 48 hrs by annexin V/FITC-propidium iodide staining-based flow cytometric method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4156737 | F | Anticlonogenic activity against human HCT116 cells after 11 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4156738 | F | Induction of mitochondrial ROS generation in human HCT116 cells at 4.2 uM after 48 hrs by MitoSOX dye-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4156739 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring increase in MDM2 expression at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4156740 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring increase in p21 level at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4156741 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring increase in GADD45 level at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4156742 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring increase in PUMA level at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4156743 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring decrease in Bcl-2 level at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4156744 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells assessed as p53 activation by measuring increase in cleaved-PARP level at 4.2 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4156745 | B | Inhibition of human MDM2-p53 interaction in Saccharomyces cerevisiae assessed as p53 induced cell growth arrest at 1 to 50 uM after 42 hrs by Yeast-based assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
20. | ALA4156747 | A | Growth inhibition of Saccharomyces cerevisiae expressing empty vector at 1 to 50 uM after 42 hrs by Yeast-based assay | Saccharomyces cerevisiae | 5 | organism-based format | Scientific Literature |