# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146647 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 10 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
2. | ALA4146648 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 1 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
3. | ALA4146649 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 0.1 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
4. | ALA4146650 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as increase in cell viability preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
5. | ALA4146651 | A | Cytotoxicity against human SH-SY5Y cells at 1 to 10 uM after 24 hrs by MTT assay | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
6. | ALA4146652 | F | Cytoprotective activity against H2O2-induced apoptosis in human SH-SY5Y cells assessed as decrease in Bax levels at 0.1 uM preincubated for 24 hrs followed by H2O2 addition measured after 1 hr by Western blot analysis | Homo sapiens | 8 | ALA4145470 | cell-based format | Scientific Literature | |
7. | ALA4146654 | F | Cytoprotective activity against H2O2-induced apoptosis in human SH-SY5Y cells assessed as increase in Bcl-2 levels at 0.1 uM preincubated for 24 hrs followed by H2O2 addition measured after 1 hr by Western blot analysis | Homo sapiens | 3 | ALA4145470 | cell-based format | Scientific Literature | |
8. | ALA4146664 | B | Induction of Akt phosphorylation in H2O2-treated human SH-SY5Y cells at 0.1 uM by ELISA | Homo sapiens | 7 | ALA4145470 | cell-based format | Scientific Literature | |
9. | ALA4146665 | B | Induction of Akt phosphorylation in H2O2-treated human SH-SY5Y cells assessed as increase in pBad levels at 0.1 uM by ELISA | Homo sapiens | 7 | ALA4145470 | cell-based format | Scientific Literature | |
10. | ALA4146669 | B | Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 0.1 uM | Homo sapiens | 9 | ALA4145470 | cell-based format | Scientific Literature |