| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4130920 | B | Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 23 | ALA4130348 | assay format | Scientific Literature | |
| 2. | ALA4130921 | B | Inhibition of recombinant full length His-tagged human BMX expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 23 | ALA4130348 | assay format | Scientific Literature | |
| 3. | ALA4130922 | B | Inhibition of recombinant full length His-tagged human BLK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 23 | ALA4130348 | assay format | Scientific Literature | |
| 4. | ALA4130923 | B | Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 23 | ALA4130348 | assay format | Scientific Literature | |
| 5. | ALA4130924 | B | Irreversible binding affinity to recombinant full length His-tagged human BTK expressed in baculovirus expression system assessed as modification of Cys481 residue containing fragment at 100 uM after 1 hr by LC/MS-MS method | Homo sapiens | 1 | ALA4130348 | assay format | Scientific Literature | |
| 6. | ALA4130925 | B | Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 2 to 60 mins followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 4 | ALA4130348 | assay format | Scientific Literature | |
| 7. | ALA4130926 | B | Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate assessed as ratio of Kinact to Ki preincubated for 2 to 60 mins followed by substrate addition measured after 1 hr by ADP-glo assay | Homo sapiens | 4 | ALA4130348 | assay format | Scientific Literature | |
| 8. | ALA4130927 | A | Antiproliferative activity against mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Mus musculus | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 9. | ALA4130928 | B | Inhibition of TEL-fused EGFR (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 10. | ALA4130929 | B | Inhibition of TEL-fused EGFR T790M mutant (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 11. | ALA4130930 | B | Inhibition of TEL-fused EGFR L858R mutant (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 12. | ALA4130931 | B | Inhibition of TEL-fused EGFR T790M/L858R mutant (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 13. | ALA4130932 | B | Inhibition of TEL-fused BMX (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 14. | ALA4130933 | B | Inhibition of TEL-fused JAK1 (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 15. | ALA4130934 | B | Inhibition of TEL-fused JAK2 (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 16. | ALA4130935 | B | Inhibition of TEL-fused JAK3 (unknown origin) expressed in mouse BA/F3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 17. | ALA4130936 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 18. | ALA4130937 | F | Antiproliferative activity against human A431 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 19. | ALA4130938 | F | Antiproliferative activity against human NCI-H460 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
| 20. | ALA4130939 | F | Antiproliferative activity against human A549 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature |
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