| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4155117 | B | Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method | Escherichia coli | 16 | ALA4152269 | assay format | Scientific Literature | |
| 2. | ALA4155118 | B | Inhibition of Escherichia coli C-terminal His6-tagged topoisomerase-4 expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method | Escherichia coli | 7 | ALA4152269 | assay format | Scientific Literature | |
| 3. | ALA4155124 | B | Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) assessed as residual activity at 1 uM preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method relative to control | Escherichia coli | 39 | ALA4152269 | assay format | Scientific Literature | |
| 4. | ALA4155126 | B | Inhibition of Staphylococcus aureus DNA gyrase B preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method | Staphylococcus aureus | 11 | ALA4152269 | single protein format | Scientific Literature | |
| 5. | ALA4155130 | B | Inhibition of Staphylococcus aureus topoisomerase-4 assessed as residual activity preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method | Staphylococcus aureus | 9 | ALA4152269 | assay format | Scientific Literature | |
| 6. | ALA4155131 | F | Growth inhibition of Staphylococcus aureus ATCC 25923 at 50 uM after 24 hrs by broth microdilution method relative to control | Staphylococcus aureus | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 7. | ALA4155132 | F | Growth inhibition of Enterococcus faecalis ATCC 29212 at 50 uM after 24 hrs by broth microdilution method relative to control | Enterococcus faecalis | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 8. | ALA4155133 | F | Growth inhibition of Escherichia coli ATCC 25922 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 9. | ALA4155134 | F | Growth inhibition of Pseudomonas aeruginosa ATCC 27853 at 50 uM after 24 hrs by broth microdilution method relative to control | Pseudomonas aeruginosa | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 10. | ALA4155135 | F | Growth inhibition of tolC deficient Escherichia coli JW5503 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 11. | ALA4155136 | F | Growth inhibition of lpxC deficient Escherichia coli JD17464 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | ALA4152269 | organism-based format | Scientific Literature | |
| 12. | ALA4155137 | F | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution method | Staphylococcus aureus | 12 | ALA4152269 | organism-based format | Scientific Literature | |
| 13. | ALA4155138 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution method | Enterococcus faecalis | 12 | ALA4152269 | organism-based format | Scientific Literature | |
| 14. | ALA4155139 | F | Antibacterial activity against tolC deficient Escherichia coli JW5503 after 18 hrs by broth microdilution method | Escherichia coli | 12 | ALA4152269 | organism-based format | Scientific Literature | |
| 15. | ALA4155140 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 18 hrs by broth microdilution method | Staphylococcus aureus | 1 | ALA4152269 | organism-based format | Scientific Literature | |
| 16. | ALA4155141 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 18 hrs by broth microdilution method | Staphylococcus aureus | 1 | ALA4152269 | organism-based format | Scientific Literature | |
| 17. | ALA4155142 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecium ATCC 700221 after 18 hrs by broth microdilution method | Enterococcus faecium | 1 | ALA4152269 | organism-based format | Scientific Literature | |
| 18. | ALA4155143 | F | Antibacterial activity against Escherichia coli ATCC 25922 up to 50 uM after 18 hrs by broth microdilution method | Escherichia coli | 1 | ALA4152269 | organism-based format | Scientific Literature | |
| 19. | ALA4155144 | F | Antibacterial activity against Escherichia coli MG1655 up to 50 uM after 18 hrs by broth microdilution method | Escherichia coli | 1 | ALA4152269 | organism-based format | Scientific Literature | |
| 20. | ALA4155145 | F | Antibacterial activity against Escherichia coli BW25113 up to 50 uM after 18 hrs by broth microdilution method | Escherichia coli | 1 | ALA4152269 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!