# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4139819 | ADME | Retention time of the compound in mouse plasma at 400 ug/ml after 3 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
2. | ALA4139820 | ADME | Retention time of the compound in mouse plasma at 400 ug/ml after 24 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
3. | ALA4139824 | Functional | Cytotoxicity against human H69 cells assessed as decrease in cell viability after 48 hrs by resazurin dye-based assay | Homo sapiens | 10 | ALA4138117 | cell-based format | Scientific Literature | |
4. | ALA4139825 | Functional | Cytotoxicity against human DMS79 cells assessed as decrease in cell viability after 48 hrs by resazurin dye-based assay | Homo sapiens | 10 | ALA4138117 | cell-based format | Scientific Literature | |
5. | ALA4139826 | Functional | Induction of apoptosis in human H69 cells assessed as loss of plasma membrane integrity at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
6. | ALA4139827 | Functional | Induction of apoptosis in human DMS79 cells assessed as loss of plasma membrane integrity at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
7. | ALA4139828 | Functional | Induction of apoptosis in human H69 cells assessed as increase in late apoptotic cells at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
8. | ALA4139829 | Functional | Induction of apoptosis in human DMS79 cells assessed as increase in late apoptotic cells at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
9. | ALA4139830 | Functional | Induction of apoptosis in human H69 cells assessed as increase in necrotic cells at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
10. | ALA4139831 | Functional | Induction of apoptosis in human DMS79 cells assessed as increase in necrotic cells at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
11. | ALA4139832 | Functional | Induction of apoptosis in human H69 cells assessed as cell shrinkage at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
12. | ALA4139833 | Functional | Induction of apoptosis in human DMS79 cells assessed as cell shrinkage at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
13. | ALA4139834 | Functional | Induction of apoptosis in human H69 cells assessed as chromatin condensation at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
14. | ALA4139835 | Functional | Induction of apoptosis in human DMS79 cells assessed as chromatin condensation at 6 uM after 48 hrs by acridine orange/ethidium bromide staining-based inverted fluorescence microscopic method | Homo sapiens | 2 | ALA4138117 | cell-based format | Scientific Literature | |
15. | ALA4139845 | ADME | Drug metabolism in neat mouse plasma at 400 ug/ml by RP-HPLC method | Mus musculus | 3 | ALA4138117 | cell-free format | Scientific Literature | |
16. | ALA4139846 | ADME | Metabolic stability in neat mouse plasma assessed as parent compound remaining at 400 ug/ml after 3 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
17. | ALA4139847 | ADME | Metabolic stability in neat mouse plasma assessed as parent compound remaining at 400 ug/ml after 24 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
18. | ALA4139848 | ADME | Metabolic stability in neat mouse plasma assessed as parent compound remaining at 400 ug/ml after 48 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
19. | ALA4139850 | ADME | Retention time of the compound in mouse plasma at 400 ug/ml after 48 hrs by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature | |
20. | ALA4139851 | ADME | Retention time of the compound in mouse plasma at 400 ug/ml measured immediately after compound addition by RP-HPLC method | Mus musculus | 4 | ALA4138117 | cell-free format | Scientific Literature |