# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4158904 | A | Inhibition of C-terminal FLAG-His-tagged full length recombinant human HDAC1 expressed in Sf21 insect cells using RHKK(Ac)AMC as substrate by fluorescence-based assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
2. | ALA4158905 | A | Inhibition of C-terminal GST-tagged recombinant human HDAC2 expressed in baculovirus infected insect cells using RHKK(Ac)AMC as substrate by fluorescence-based assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
3. | ALA4158906 | A | Inhibition of recombinant human HDAC3/NCOR2 expressed in baculovirus infected insect cells using RHKK(Ac)AMC as substrate by fluorescence-based assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
4. | ALA4158907 | B | Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected insect cells using RHKK(Ac)AMC as substrate by fluorescence-based assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
5. | ALA4158908 | B | Inhibition of C-terminal His-tagged recombinant human HDAC8 expressed in baculovirus infected insect cells using RHKK(Ac)AMC as substrate by fluorescence-based assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
6. | ALA4158909 | B | Inhibition of HDAC6 in human HL60 cells assessed as increase in acetyl-alpha tubulin expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
7. | ALA4158910 | B | Inhibition of HDAC6 in human SEM cells assessed as increase in acetyl-alpha tubulin expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
8. | ALA4158911 | B | Inhibition of HDAC6 in imatinib-resistant human SUP-B15 cells assessed as increase in acetyl-alpha tubulin expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
9. | ALA4158912 | B | Inhibition of HDAC6 in human HL60 cells assessed as increase in acetyl-histone H3 expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
10. | ALA4158913 | B | Inhibition of HDAC6 in human SEM cells assessed as increase in acetyl-histone H3 expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
11. | ALA4158914 | B | Inhibition of HDAC6 in imatinib-resistant human SUP-B15 cells assessed as increase in acetyl-histone H3 expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 2 | ALA4152390 | cell-based format | Scientific Literature | |
12. | ALA4158915 | B | Inhibition of HDAC6/chymotrypsin-like activity of 20S proteasome in human HL60 cells assessed as increase in cleaved PARP expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature | |
13. | ALA4158916 | B | Inhibition of HDAC6/chymotrypsin-like activity of 20S proteasome in human SEM cells assessed as increase in cleaved PARP expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature | |
14. | ALA4158917 | B | Inhibition of HDAC6/chymotrypsin-like activity of 20S proteasome in imatinib-resistant human SUP-B15 cells assessed as increase in cleaved PARP expression at 0.1 to 10 uM after 24 hrs by immunoblot assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature | |
15. | ALA4158924 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVY aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 4 | ALA4152390 | cell-based format | Scientific Literature | |
16. | ALA4158925 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in human SEM cells using Suc-LLVY aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 4 | ALA4152390 | cell-based format | Scientific Literature | |
17. | ALA4158926 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in imatinib-resistant human SUP-B15 cells using Suc-LLVY aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 4 | ALA4152390 | cell-based format | Scientific Literature | |
18. | ALA4158927 | B | Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells at 4 nM to 25 uM using Z-LRR-aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature | |
19. | ALA4158928 | B | Inhibition of trypsin-like activity of 20S proteasome in human SEM cells at 4 nM to 25 uM using Z-LRR-aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature | |
20. | ALA4158929 | B | Inhibition of trypsin-like activity of 20S proteasome in human imatinib-resistant SUP-B15 cells at 4 nM to 25 uM using Z-LRR-aminoluciferin as substrate after 2 hrs by proteasome-Glo assay | Homo sapiens | 1 | ALA4152390 | cell-based format | Scientific Literature |