# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4147165 | B | Inhibition of bacterial VIM2 (27 to 266 residues) expressed in Escherichia coli Transetta (DE3) cells using FC-5 as substrate by fluorescence assay | Bacteria | 10 | cell-based format | Scientific Literature | ||
2. | ALA4147166 | B | Inhibition of bacterial NDM1 (1 to 270 residues) expressed in Escherichia coli Transetta (DE3) cells using FC-5 as substrate by fluorescence assay | Bacteria | 10 | cell-based format | Scientific Literature | ||
3. | ALA4147169 | A | Toxicity in FLK-1 promoter EGFP transgenic zebrafish embryos assessed as effect on morphology at 20 uM incubated for 4 to 96 hrs post fertilization by fluorescence microscopic analysis | Danio rerio | 2 | organism-based format | Scientific Literature | ||
4. | ALA4147170 | B | Inhibition of bacterial VIM2 (27 to 266 residues) expressed in Escherichia coli Transetta (DE3) cells using FC-5 as substrate in presence of 1 uM Zn2+ by fluorescence assay | Bacteria | 2 | cell-based format | Scientific Literature | ||
5. | ALA4147171 | B | Inhibition of bacterial VIM2 (27 to 266 residues) expressed in Escherichia coli Transetta (DE3) cells using FC-5 as substrate in presence of 100 uM Zn2+ by fluorescence assay | Bacteria | 2 | cell-based format | Scientific Literature | ||
6. | ALA4147174 | B | Reversible inhibition of bacterial VIM2 (27 to 266 residues) expressed in Escherichia coli Transetta (DE3) cells at 0.14 uM using FC-5 as substrate up to 500 secs by jump dilution assay | Bacteria | 1 | cell-based format | Scientific Literature | ||
7. | ALA4147175 | A | Cytotoxicity against HEK293T cells assessed as reduction in cell viability at 50 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4147176 | A | Toxicity in FLK-1 promoter EGFP transgenic zebrafish embryos assessed as death at 20 uM incubated for 4 to 96 hrs post fertilization by fluorescence microscopic analysis | Danio rerio | 2 | organism-based format | Scientific Literature | ||
9. | ALA4147177 | A | Toxicity in FLK-1 promoter EGFP transgenic zebrafish embryos assessed as limited mobility at 20 uM incubated for 4 to 96 hrs post fertilization by fluorescence microscopic analysis | Danio rerio | 2 | organism-based format | Scientific Literature | ||
10. | ALA4147178 | B | Inhibition of Escherichia coli VIM2 expressed in Escherichia coli DH5alpha assessed as potentiation of meropenem induced antibacterial activity by measuring meropenem MIC at 100 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = 16 microg/ml) | Escherichia coli | 2 | assay format | Scientific Literature | ||
11. | ALA4147179 | B | Inhibition of Escherichia coli VIM2 expressed in Escherichia coli DH5alpha assessed as potentiation of meropenem induced antibacterial activity by measuring meropenem MIC at 200 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = 16 microg/ml) | Escherichia coli | 2 | assay format | Scientific Literature | ||
12. | ALA4147180 | B | Inhibition of Escherichia coli VIM2 expressed in Escherichia coli DH5alpha assessed as potentiation of meropenem induced antibacterial activity by measuring meropenem MIC at 500 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = 16 microg/ml) | Escherichia coli | 2 | assay format | Scientific Literature | ||
13. | ALA4147181 | A | Growth inhibition of Escherichia coli DH5alpha after 16 to 20 hrs by CLSI broth microdilution method | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
14. | ALA4147182 | F | Potentiation of meropenem induced antibacterial activity against Escherichia coli DH5alpha by measuring meropenem MIC at 100 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = <0.25 microg/ml) | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
15. | ALA4147183 | F | Potentiation of meropenem induced antibacterial activity against Escherichia coli DH5alpha by measuring meropenem MIC at 200 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = <0.25 microg/ml) | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
16. | ALA4147184 | F | Potentiation of meropenem induced antibacterial activity against Escherichia coli DH5alpha by measuring meropenem MIC at 500 uM after 16 to 20 hrs by CLSI broth microdilution method (Rvb = <0.25 microg/ml) | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
17. | ALA4147185 | B | Inhibition of Escherichia coli VIM2 expressed in Escherichia coli DH5alpha assessed as potentiation of meropenem induced antibacterial activity by measuring fold reduction of meropenem MIC after 16 to 20 hrs by CLSI broth microdilution method relative to control | Escherichia coli | 2 | assay format | Scientific Literature | ||
18. | ALA4147186 | A | Toxicity in FLK-1 promoter EGFP transgenic zebrafish embryos assessed as effect on angiogenesis at 20 uM incubated for 4 to 96 hrs post fertilization by fluorescence microscopic analysis | Danio rerio | 2 | organism-based format | Scientific Literature | ||
19. | ALA4147187 | A | Growth inhibition of Escherichia coli DH5alpha expressing Escherichia coli VIM2 after 16 to 20 hrs by CLSI broth microdilution method | Escherichia coli | 2 | organism-based format | Scientific Literature |