| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4141928 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as increase in dead cells at 50 uM after 24 hrs by Calcein-AM/ethidium bromide staining-based fluorescence assay (Rvb = 3%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 2. | ALA4141929 | Functional | Induction of apoptosis in human CHL-1 cells harboring wild type BRAF assessed as increase in dead cells at 25 uM after 24 hrs by Calcein-AM/ethidium bromide staining-based fluorescence assay (Rvb = 2%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 3. | ALA4141930 | Functional | Induction of apoptosis in human CHL-1 cells harboring wild type BRAF assessed as increase in dead cells at 50 uM after 24 hrs by Calcein-AM/ethidium bromide staining-based fluorescence assay (Rvb = 2%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 4. | ALA4141931 | Functional | Antiproliferative activity against human CHL-1 cells harboring wild type BRAF after 72 hrs by MTT assay | Homo sapiens | 25 | ALA4138168 | cell-based format | Scientific Literature | |
| 5. | ALA4141932 | Functional | Cytotoxicity against human UACC-903 cells assessed as cell viability at 25 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 25 | ALA4138168 | cell-based format | Scientific Literature | |
| 6. | ALA4141933 | Functional | Antiproliferative activity against human CHL-1 cells harboring wild type BRAF after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 7. | ALA4141934 | Functional | Antiproliferative activity against human 1205 Lu cells after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 8. | ALA4141935 | Functional | Antiproliferative activity against human A375M cells after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 9. | ALA4141936 | Functional | Antiproliferative activity against human UACC-903 cells harboring BRAF mutant after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 10. | ALA4141937 | Functional | Antiproliferative activity against human WM266.4 cells after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 11. | ALA4141938 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as increase in dead cells at 25 uM after 24 hrs by Calcein-AM/ethidium bromide staining-based fluorescence assay (Rvb = 3%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 12. | ALA4141939 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as viable cells at 5 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 95.64%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 13. | ALA4141940 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as early apoptotic cells at 5 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 2.68%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 14. | ALA4141941 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as late apoptotic cells at 5 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 1.56%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 15. | ALA4141942 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as necrotic cells at 5 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 0.12%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 16. | ALA4141943 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as viable cells at 25 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 95.64%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 17. | ALA4141944 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as early apoptotic cells at 25 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 2.68%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 18. | ALA4141945 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as late apoptotic cells at 25 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 1.56%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 19. | ALA4141946 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as necrotic cells at 25 uM after 24 hrs by Annexin V/7-AAD staining-based assay (Rvb = 0.12%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature | |
| 20. | ALA4141947 | Functional | Induction of apoptosis in human UACC-903 cells harboring BRAF mutant assessed as dead cells level at 5 uM after 24 hrs by AAD dye containing caspase 3/7 activity assay (Rvb = 0.06%) | Homo sapiens | 2 | ALA4138168 | cell-based format | Scientific Literature |
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