# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4155124 | B | Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) assessed as residual activity at 1 uM preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method relative to control | Escherichia coli | 39 | assay format | Scientific Literature | ||
2. | ALA4155131 | F | Growth inhibition of Staphylococcus aureus ATCC 25923 at 50 uM after 24 hrs by broth microdilution method relative to control | Staphylococcus aureus | 28 | organism-based format | Scientific Literature | ||
3. | ALA4155132 | F | Growth inhibition of Enterococcus faecalis ATCC 29212 at 50 uM after 24 hrs by broth microdilution method relative to control | Enterococcus faecalis | 28 | organism-based format | Scientific Literature | ||
4. | ALA4155133 | F | Growth inhibition of Escherichia coli ATCC 25922 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | organism-based format | Scientific Literature | ||
5. | ALA4155134 | F | Growth inhibition of Pseudomonas aeruginosa ATCC 27853 at 50 uM after 24 hrs by broth microdilution method relative to control | Pseudomonas aeruginosa | 28 | organism-based format | Scientific Literature | ||
6. | ALA4155135 | F | Growth inhibition of tolC deficient Escherichia coli JW5503 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | organism-based format | Scientific Literature | ||
7. | ALA4155136 | F | Growth inhibition of lpxC deficient Escherichia coli JD17464 at 50 uM after 24 hrs by broth microdilution method relative to control | Escherichia coli | 28 | organism-based format | Scientific Literature | ||
8. | ALA4666308 | F | Antibacterial activity against efflux pump d effect ive Escherichia coli JW5503 harbouring tolC mutant assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Escherichia coli | 34 | organism-based format | Scientific Literature | ||
9. | ALA4666309 | F | Antibacterial activity against outer membrane impaired Escherichia coli JD17464 harboring lpxC mutant assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Escherichia coli | 34 | organism-based format | Scientific Literature | ||
10. | ALA4666310 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Pseudomonas aeruginosa | 34 | organism-based format | Scientific Literature | ||
11. | ALA4666311 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Staphylococcus aureus | 34 | organism-based format | Scientific Literature | ||
12. | ALA4666312 | F | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Klebsiella pneumoniae | 34 | organism-based format | Scientific Literature | ||
13. | ALA4666313 | F | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Escherichia coli | 34 | organism-based format | Scientific Literature | ||
14. | ALA4666314 | F | Antibacterial activity against Enterococcus faecium ATCC 35667 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Enterococcus faecium | 34 | organism-based format | Scientific Literature | ||
15. | ALA4666315 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Enterococcus faecalis | 34 | organism-based format | Scientific Literature | ||
16. | ALA4666316 | F | Antibacterial activity against Enterobacter aerogenes ATCC 13408 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Klebsiella aerogenes | 34 | organism-based format | Scientific Literature | ||
17. | ALA4666317 | F | Antibacterial activity against Acinetobacter baumannii ATCC 19606 assessed as bacterial growth inhibition at 50 uM incubated for 24 hrs by CLSI protocol based broth microdilution assay relative to control | Acinetobacter baumannii | 34 | organism-based format | Scientific Literature | ||
18. | ALA4666342 | B | Inhibition of Escherichia coli DNA gyrase assessed as residual activity at 1 uM using biotinylated oligonucleotide as substrate incubated for 30 mins in presence of ATP by fluorescence-based microplate reader assay relative to control | Escherichia coli | 13 | protein complex format | Scientific Literature |