| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4138488 | B | Inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of homocysteine and lead nitrate followed by cysteine addition | Homo sapiens | 12 | ALA4138050 | single protein format | Scientific Literature | |
| 2. | ALA4138489 | B | Inhibition of N-terminal His-tagged CSE extracted from human HepG2 cells expressed in Escherichia coli BL21 (DE3) using cysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of lead nitrate followed by cysteine addition | Homo sapiens | 9 | ALA4138050 | assay format | Scientific Literature | |
| 3. | ALA4138491 | B | Reversible inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production at 100 uM preincubated for 1 hr followed by ultrafiltration for 5 times | Homo sapiens | 11 | ALA4138050 | single protein format | Scientific Literature | |
| 4. | ALA4138492 | F | Antiproliferative activity against human HT-29 cells assessed as decrease in cell viability after 24 hrs by CCK8 assay | Homo sapiens | 7 | ALA4138050 | cell-based format | Scientific Literature |
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