| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4155463 | B | Inhibition of human placental cytosolic 17beta-HSD1 using [2,4,6,7-3H]-labeled E1/E1 as substrate and NADH at 1 uM after 10 mins by HPLC based radioflow detection method | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 2. | ALA4155464 | P | Solubility of the compound in PBS at 200 uM at pH 7.4 measured after 24 hrs | 15 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4155465 | B | Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NAD measured continuously for 15 mins by fluorimetric method | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 4. | ALA4155468 | B | Inhibition of human placental cytosolic 17beta-HSD2 using [2,4,6,7-3H]-labeled E2/E2 as substrate and NADH at 1 uM after 10 mins by HPLC based radioflow detection method | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 5. | ALA4155469 | B | Inhibition of human full length N-terminal GST-tagged 17beta-HSD10 expressed in Escherichia coli BL21 DE3 Codon plus using [6,7-3H]-labeled E2/E2 as substrate and NADH at 1 uM after 30 mins by HPLC based radioflow detection method | Homo sapiens | 14 | assay format | Scientific Literature | ||
| 6. | ALA4155471 | A | Agonist activity at ERalpha (unknown origin) expressed in human U2OS cells after 24 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4155473 | A | Cytotoxicity against HEK293 cells assessed as cell survival at 20 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature |
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