| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4146647 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 10 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
| 2. | ALA4146648 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 1 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
| 3. | ALA4146649 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as cell viability at 0.1 uM preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay (Rvb = 37.88 +/- 8.52%) | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
| 4. | ALA4146650 | F | Cytoprotective activity against H2O2-induced oxidative stress in human SH-SY5Y cells assessed as increase in cell viability preincubated for 24 hrs followed by H2O2 addition and measured after 1 hr by MTT assay | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
| 5. | ALA4146651 | A | Cytotoxicity against human SH-SY5Y cells at 1 to 10 uM after 24 hrs by MTT assay | Homo sapiens | 18 | ALA4145470 | cell-based format | Scientific Literature | |
| 6. | ALA4146658 | B | Inhibition of H2O2-induced p38 MAPK phosphorylation in human SH-SY5Y cells at 1 uM | Homo sapiens | 1 | ALA4145470 | cell-based format | Scientific Literature | |
| 7. | ALA4146662 | F | Cytoprotective activity against H2O2-induced apoptosis in human SH-SY5Y cells assessed as relative cleaved PARP levels at 1 uM (Rvb = 0.725 +/- 0.06 No_unit) | Homo sapiens | 1 | ALA4145470 | cell-based format | Scientific Literature | |
| 8. | ALA4146663 | F | Cytoprotective activity against H2O2-induced apoptosis in human SH-SY5Y cells assessed as relative cleaved caspase-3 levels at 1 uM (Rvb = 0.875 +/- 0.035 No_unit) | Homo sapiens | 1 | ALA4145470 | cell-based format | Scientific Literature | |
| 9. | ALA4146666 | B | Induction of Akt phosphorylation in H2O2-treated human SH-SY5Y cells at 1 uM by ELISA | Homo sapiens | 1 | ALA4145470 | cell-based format | Scientific Literature | |
| 10. | ALA4146667 | B | Induction of Akt phosphorylation in H2O2-treated human SH-SY5Y cells assessed as increase in pBad levels at 1 uM by ELISA | Homo sapiens | 1 | ALA4145470 | cell-based format | Scientific Literature | |
| 11. | ALA4146668 | B | Inhibition of H2O2-induced eIF2alpha phosphorylation in human SH-SY5Y cells at 1 uM | Homo sapiens | 5 | ALA4145470 | cell-based format | Scientific Literature | |
| 12. | ALA4146673 | B | Cytoprotective activity against H2O2-induced apoptosis in human SH-SY5Y cells assessed as relative cleaved caspase-7 levels at 1 uM (Rvb = 1.025 +/- 0.120 No_unit) | Homo sapiens | 2 | ALA4145470 | cell-based format | Scientific Literature | |
| 13. | ALA4146675 | B | Inhibition of H2O2-induced p44/42 MAPK phosphorylation in human SH-SY5Y cells at 1 uM | Homo sapiens | 3 | ALA4145470 | cell-based format | Scientific Literature |
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