| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4154870 | B | Inhibition of His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by AlphaScreen assay | Homo sapiens | 35 | ALA4152259 | assay format | Scientific Literature | |
| 2. | ALA4154871 | B | Binding affinity to His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 34 | ALA4152259 | assay format | Scientific Literature | |
| 3. | ALA4154872 | B | Inhibition of His6-tagged human CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by AlphaScreen assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 4. | ALA4154873 | B | Binding affinity to His6-tagged human BRD2 bromodomain-1 (K77 to N194 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 5. | ALA4154874 | B | Binding affinity to His6-tagged human BRD2 bromodomain-2 expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 6. | ALA4154875 | B | Binding affinity to His6-tagged human BRD3 bromodomain-1 (P24 to E144 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 7. | ALA4154876 | B | Binding affinity to His6-tagged human BRD3 bromodomain-2 expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 8. | ALA4154877 | B | Binding affinity to His6-tagged human BRD4 bromodomain-2 expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 9. | ALA4154878 | B | Binding affinity to His6-tagged human BRDT bromodomain-1 (N21 to E137 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 10. | ALA4154879 | B | Binding affinity to His6-tagged human EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 11. | ALA4154880 | B | Binding affinity to His6-tagged human CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 12. | ALA4154881 | B | Binding affinity to His6-tagged human BRD9 (L14 to Q134 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 13. | ALA4154882 | B | Binding affinity to TIF1 (unknown origin) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | single protein format | Scientific Literature | |
| 14. | ALA4154883 | B | Binding affinity to His6-tagged human BAZ2B (S1858 to S1972 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 15. | ALA4154884 | B | Binding affinity to His6-tagged human TAF1 (R1377 to D1503 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 16. | ALA4154885 | B | Binding affinity to His6-tagged human ASH1L (E2433 to E2564 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 17. | ALA4154886 | B | Binding affinity to His6-tagged human PCAF (G715 to D831 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 200 uM by SYPRO orange dye based fluorescence assay | Homo sapiens | 7 | ALA4152259 | assay format | Scientific Literature | |
| 18. | ALA4154887 | B | Binding affinity to His6-tagged human BRD4 bromodomain-1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) by ITC | Homo sapiens | 3 | ALA4152259 | assay format | Scientific Literature | |
| 19. | ALA4154889 | F | Antiproliferative activity against human LNCAP cells treated at 12 hrs post cell seeding measured at 72 to 144 hrs post cell seeding by Cell-Titer Glo assay | Homo sapiens | 11 | ALA4152259 | cell-based format | Scientific Literature | |
| 20. | ALA4154890 | F | Antiproliferative activity against human C4-2B cells treated at 12 hrs post cell seeding measured at 72 to 144 hrs post cell seeding by Cell-Titer Glo assay | Homo sapiens | 11 | ALA4152259 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!