# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4154035 | B | Binding affinity to N-terminal His6-tagged p53 DNA binding domain Y220C mutant (94 to 312 residues) (unknown origin) expressed in Escherichia coli C41 assessed as change in melting temperature at 250 uM by SYPRO orange dye based DSF analysis | Homo sapiens | 21 | ALA4152234 | assay format | Scientific Literature | |
2. | ALA4154039 | B | Binding affinity to N-terminal His6-tagged p53 DNA binding domain Y220C mutant (94 to 312 residues) (unknown origin) expressed in Escherichia coli C41 by ITC | Homo sapiens | 20 | ALA4152234 | assay format | Scientific Literature | |
3. | ALA4154041 | F | Antiproliferative activity against human NUGC3 cells harboring p53 Y220C mutant after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
4. | ALA4154042 | A | Antiproliferative activity against human NUGC4 cells harboring wild-type p53 after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
5. | ALA4154043 | A | Antiproliferative activity against human WI38 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
6. | ALA4154044 | F | Antiproliferative activity against human BxPC3 cells harboring p53 Y220C mutant after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
7. | ALA4154045 | F | Antiproliferative activity against human SW1088 cells harboring p53 Y220C mutant after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
8. | ALA4154046 | F | Antiproliferative activity against human HuH7 cells harboring p53 Y220C mutant after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature | |
9. | ALA4154047 | A | Antiproliferative activity against human HuH6 cells harboring wild-type p53 after 72 hrs by CellTiter-Glo assay | Homo sapiens | 6 | ALA4152234 | cell-based format | Scientific Literature |