# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4148151 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 10 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control | Mus musculus | 8 | cell-based format | Scientific Literature | ||
2. | ALA4148152 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 1 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA4148153 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 5 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
4. | ALA4148154 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 20 uM preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA4148155 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as reduction in PGE2 production preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by enzyme immunoassay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA4148156 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS induced cox-2 expression at 5 to 20 uM preincubated for 2 hrs followed by LPS challenge measured after 24 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4148157 | A | Inhibition of COX-1 in mouse RAW264.7 cells assessed as reduction in PGE2 production at 10 uM after 24 hrs by enzyme immunoassay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4148158 | A | Down regulation of COX-1 expression in mouse RAW264.7 cells at 10 uM after 24 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature |