| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4136260 | B | Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 2. | ALA4136261 | B | Inhibition of recombinant PDGFRbeta (unknown origin) by off-chip mobility shift assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 3. | ALA4136262 | B | Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 4. | ALA4136263 | B | Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 96 aqueous one solution based assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA4136264 | B | Inhibition of human ERG | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 6. | ALA4136271 | B | Inhibition of recombinant c-KIT (unknown origin) at 1 uM by off-chip mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA4136274 | B | Inhibition of recombinant PDGFRalpha (unknown origin) at 1 uM by off-chip mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA4136277 | B | Inhibition of recombinant FLT3 (unknown origin) at 1 uM by off-chip mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4136278 | B | Inhibition of recombinant FYN (unknown origin) at 1 uM by off-chip mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA4136280 | B | Inhibition of recombinant RET (unknown origin) at 1 uM by off-chip mobility shift assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 11. | ALA4136285 | A | Half life in CD1 mouse at 50 mg/kg, iv by UFLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4136286 | A | Half life in Sprague-Dawley rat at 10 mg/kg, iv by UFLC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4136287 | A | Half life in Beagle dog rat at 20 mg/kg, iv by UFLC-MS/MS analysis | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4136288 | A | AUC in CD1 mouse at 50 mg/kg, iv by UFLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4136289 | A | AUC in Sprague-Dawley rat at 10 mg/kg, iv by UFLC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4136290 | A | AUC in Beagle dog rat at 20 mg/kg, iv by UFLC-MS/MS analysis | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4136291 | A | Oral bioavailability in CD1 mouse at 50 mg/kg administered via gavage by UFLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4136292 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg administered via gavage by UFLC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4136293 | A | Oral bioavailability in Beagle dog rat at 20 mg/kg administered via gavage by UFLC-MS/MS analysis | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4136294 | F | Antifibrotic activity in BLM-induced chronic pulmonary fibrosis C57 mouse model assessed as increase in survival rate administered qd measured up to 28 days | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!