| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4145406 | B | Mixed type inhibition of kallikrein 7 (unknown origin) using fluorescently labeled peptide substrate by fluorescence assay based Michaelis-Menten kinetic plot analysis | Homo sapiens | 2 | ALA4138319 | single protein format | Scientific Literature | |
| 2. | ALA4145407 | F | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4138319 | cell-based format | Scientific Literature | |
| 3. | ALA4145410 | B | Inhibition of kallikrein 7 (unknown origin) by fluorescence assay | Homo sapiens | 3 | ALA4138319 | single protein format | Scientific Literature | |
| 4. | ALA4145411 | B | Inhibition of chymase (unknown origin) by fluorescence assay | Homo sapiens | 3 | ALA4138319 | single protein format | Scientific Literature | |
| 5. | ALA4145412 | B | Inhibition of human caspase 14 using Ac-WEHD-AMC fluorogenic peptide as substrate by fluorescence assay | Homo sapiens | 3 | ALA4138319 | single protein format | Scientific Literature | |
| 6. | ALA4145413 | B | Inhibition of chymotrypsin (unknown origin) by fluorescence assay | Homo sapiens | 3 | ALA4138319 | assay format | Scientific Literature | |
| 7. | ALA4145414 | B | Inhibition of recombinant human kallikrein 7 assessed as decrease in cleavage of desmoglein-2 at 10 uM after 30 mins or 2 hrs by silver staining based SDS-PAGE analysis | Homo sapiens | 1 | ALA4138319 | single protein format | Scientific Literature | |
| 8. | ALA4145415 | B | Inhibition of recombinant human kallikrein 7 assessed as decrease in cleavage of E-cadherin at 10 uM after 30 mins or 2 hrs by silver staining based SDS-PAGE analysis | Homo sapiens | 1 | ALA4138319 | single protein format | Scientific Literature | |
| 9. | ALA4145416 | B | Inhibition of kallikrein 7-mediated Dsg-2 shedding in human MDA-MB-468 cells at 0.01 to 10 uM incubated for 48 hrs by ELISA | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 10. | ALA4145417 | F | Antimigratory activity against human MDA-MB-468 cells at 0.1 to 10 uM after 48 hrs | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 11. | ALA4145418 | F | Agonist activity at human CXCR7 expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment at 10 uM by chemiluminescence method | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 12. | ALA4145419 | F | Antagonist activity at human CCR10 expressed in human U2OS cells assessed as inhibition of CCL27-induced beta-arrestin recruitment at 10 uM pre-incubated for 30 mins before CCL27 stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 13. | ALA4145420 | F | Antagonist activity at human OXTR expressed in CHOK1 cells assessed as oxytocin-induced beta-arrestin recruitment at 10 uM pre-incubated for 30 mins before oxytocin stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 14. | ALA4145421 | F | Antagonist activity at human TACR2 expressed in CHOK1 cells assessed as substance P-induced beta-arrestin recruitment at 10 uM pre-incubated for 30 mins before substance P stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 15. | ALA4145422 | F | Antagonist activity at human SSTR3 expressed in HEK293 cells assessed as [Tyr1]-somatostatin 14-induced beta-arrestin recruitment at 10 uM pre-incubated for 30 mins before [Tyr1]-somatostatin 14 stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 1 | ALA4138319 | cell-based format | Scientific Literature | |
| 16. | ALA4145423 | F | Agonist activity at human CXCR7 expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment by chemiluminescence method | Homo sapiens | 7 | ALA4138319 | cell-based format | Scientific Literature | |
| 17. | ALA4145424 | F | Antagonist activity at human CCR10 expressed in human U2OS cells assessed as inhibition of CCL27-induced beta-arrestin recruitment pre-incubated for 30 mins before CCL27 stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 7 | ALA4138319 | cell-based format | Scientific Literature | |
| 18. | ALA4145425 | F | Antagonist activity at human OXTR expressed in CHOK1 cells assessed as oxytocin-induced beta-arrestin recruitment pre-incubated for 30 mins before oxytocin stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 7 | ALA4138319 | cell-based format | Scientific Literature | |
| 19. | ALA4145426 | F | Antagonist activity at human TACR2 expressed in CHOK1 cells assessed as substance P-induced beta-arrestin recruitment pre-incubated for 30 mins before substance P stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 7 | ALA4138319 | cell-based format | Scientific Literature | |
| 20. | ALA4145427 | F | Antagonist activity at human SSTR3 expressed in HEK293 cells assessed as [Tyr1]-somatostatin 14-induced beta-arrestin recruitment pre-incubated for 30 mins before [Tyr1]-somatostatin 14 stimulation for 90 or 180 mins by chemiluminescence method | Homo sapiens | 7 | ALA4138319 | cell-based format | Scientific Literature |
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