# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4145044 | B | Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISA | Homo sapiens | 15 | ALA4138308 | protein complex format | Scientific Literature | |
2. | ALA4145045 | B | Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISA | Homo sapiens | 15 | ALA4138308 | protein complex format | Scientific Literature | |
3. | ALA4145046 | B | Displacement of p53 from MDM2 in human U87MG cells incubated for 10 mins by sandwich ELISA method | Homo sapiens | 14 | ALA4138308 | cell-based format | Scientific Literature | |
4. | ALA4145047 | B | Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA method | Homo sapiens | 14 | ALA4138308 | cell-based format | Scientific Literature | |
5. | ALA4145059 | B | Inhibition of alphaVbeta3 integrin/alpha5beta1 integrin/MDM2/MDM4 in human U87MG cells assessed as increase in p53 accumulation at 100 nM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
6. | ALA4145066 | B | Inhibition of alphaVbeta3 integrin/alpha5beta1 integrin/MDM2/MDM4 in human U87MG cells assessed as increase in MDM2 mRNA expression at 100 nM after 8 hrs by RT-PCR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
7. | ALA4145067 | B | Inhibition of alphaVbeta3 integrin/alpha5beta1 integrin/MDM2/MDM4 in human U87MG cells assessed as increase in MDM2 mRNA expression at 100 nM after 24 hrs by RT-PCR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
8. | ALA4145080 | B | Inhibition of alphaVbeta3 integrin/alpha5beta1 integrin/MDM2/MDM4 in human U87MG cells assessed as increase in PUMA mRNA expression at 100 nM after 24 hrs by RT-PCR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
9. | ALA4145084 | B | Inhibition of alphaVbeta3 integrin/alpha5beta1 integrin/MDM2/MDM4 in human U87MG cells assessed as increase in p21 mRNA expression at 100 nM after 24 hrs by RT-PCR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
10. | ALA4145085 | F | Antiproliferative activity against human U87MG cells after 72 hrs by MTS assay | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
11. | ALA4145092 | F | Antiproliferative activity against human T98G cells harboring p53 mutant at micromolar concentration after 72 hrs by MTS assay | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
12. | ALA4145093 | F | Antiproliferative activity against human T98G cells harboring p53 mutant at nanomolar concentration after 72 hrs by MTS assay | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
13. | ALA4145097 | F | Cell cycle arrest in human U87MG cells assessed as accumulation at G0/G1 phase at 100 nM after 24 hrs | Homo sapiens | 2 | ALA4138308 | cell-based format | Scientific Literature | |
14. | ALA4145098 | F | Anti-invasive activity in human U87MG cells at 10 uM after 24 hrs by transwell assay | Homo sapiens | 4 | ALA4138308 | cell-based format | Scientific Literature | |
15. | ALA4145102 | B | Binding affinity to 15N-labeled MDM2 (unknown origin) expressed in Escherichia coli BL21-Gold(DE3) cells at 200 uM by 2D 1H-15N HSQC NMR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
16. | ALA4145103 | B | Binding affinity to 15N-labeled MDM2 (unknown origin) expressed in Escherichia coli BL21-Gold(DE3) cells at 200 uM in presence of MDM2 inhibitor nutlin-3 by 2D 1H-15N HSQC NMR method | Homo sapiens | 1 | ALA4138308 | cell-based format | Scientific Literature | |
17. | ALA5164630 | B | Inhibition of MDM2/p53 interaction in human U-87 MG cells incubated for 10 mins by immuno-enzymatic assay | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature | |
18. | ALA5164650 | B | Inhibition of MDM4/p53 interaction in human SH-SY5Y cells incubated for 10 mins by quantitative immuno-enzymatic assay | Homo sapiens | 1 | ALA5154862 | cell-based format | Scientific Literature |