# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4144878 | B | Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected Sf9 insect cells using histone H3 (1 to 50 residues)-GGK as substrate after 2 hrs in presence of SAM by fluorescence assay | Homo sapiens | 25 | ALA4138300 | cell-based format | Scientific Literature | |
2. | ALA4144879 | F | Cytotoxicity against human Pfeiffer cells assessed as decrease in cell viability after 5 days by CellTiter-Glo reagent based luminescence assay | Homo sapiens | 25 | ALA4138300 | cell-based format | Scientific Literature | |
3. | ALA4144882 | A | Half life in human liver microsomes | Homo sapiens | 2 | ALA4138300 | microsome format | Scientific Literature | |
4. | ALA4144883 | A | Half life in rat liver microsomes | Rattus norvegicus | 2 | ALA4138300 | microsome format | Scientific Literature | |
5. | ALA4144896 | A | AUC (0 to t) in ICR mouse at 10 mg/kg administered via oral gavage | Mus musculus | 2 | ALA4138300 | organism-based format | Scientific Literature |