| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4157756 | B | Inhibition of BACE 1 (unknown origin) at 50 uM using Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assay relative to control | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 2. | ALA4157757 | B | Inhibition of BACE 1 (unknown origin) using 250 nM of Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 3. | ALA4157759 | B | Inhibition of BACE 1 (unknown origin) at 10 to 50 uM using Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assay relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 4. | ALA4157760 | B | Metal chelating activity assessed as compound-Cu2+ adduct formation by spectrophotometric analysis | 5 | assay format | Scientific Literature | |||
| 5. | ALA4157761 | B | Metal chelating activity assessed as compound-Cu2+ adduct formation at 20 uM by spectrophotometric titration analysis | 7 | assay format | Scientific Literature | |||
| 6. | ALA4157762 | B | Metal chelating activity assessed as inhibition of Cu2+ induced amyloid beta (1 to 40) aggregation by measuring decrease in ROS production at 2 equiv after 75 mins by fluorescence assay | 7 | assay format | Scientific Literature | |||
| 7. | ALA4157763 | F | Antioxidant activity assessed as AAPH radical scavenging activity at 1 to 16 uM by ORAC assay | 7 | assay format | Scientific Literature | |||
| 8. | ALA4157765 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 3 by thioflavin-T based assay (Rvb = 33.64 +/- 5.80 No_unit) | 7 | assay format | Scientific Literature | |||
| 9. | ALA4157766 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as aggregation level at 100 uM measured on day 3 by UV-visible turbidity method (Rvb = 100 +/- 17.24%) | 7 | assay format | Scientific Literature | |||
| 10. | ALA4157767 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 7 by thioflavin-T based assay (Rvb = 181.04 +/- 1.74 No_unit) | 7 | assay format | Scientific Literature | |||
| 11. | ALA4157768 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as aggregation level at 100 uM measured on day 7 by UV-visible turbidity method (Rvb = 100 +/- 0.96%) | 7 | assay format | Scientific Literature | |||
| 12. | ALA4157769 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 10 by thioflavin-T based assay (Rvb = 412.11 +/- 35.93 No_unit) | 7 | assay format | Scientific Literature | |||
| 13. | ALA4157770 | B | Inhibition of Cu2+ induced amyloid beta (1 to 40) fibril aggregation assessed as aggregation level at 100 uM measured on day 10 by UV-visible turbidity method (Rvb = 100 +/- 8.72%) | 7 | assay format | Scientific Literature | |||
| 14. | ALA4157771 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 3 by thioflavin-T based assay (Rvb = 251.22 +/- 0.35 No_unit) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 15. | ALA4157772 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as aggregation level at 100 uM measured on day 3 by UV-visible turbidity method (Rvb = 100 +/- 0.14%) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 16. | ALA4157773 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 7 by thioflavin-T based assay (Rvb = 391.27 +/- 8.68 No_unit) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 17. | ALA4157774 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as aggregation level at 100 uM measured on day 7 by UV-visible turbidity method (Rvb = 100 +/- 2.22%) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 18. | ALA4157775 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as fluorescence emission at 100 uM measured on day 10 by thioflavin-T based assay (Rvb = 408.94 +/- 32 No_unit) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 19. | ALA4157776 | B | Inhibition of self-induced amyloid beta (1 to 40) (unknown origin) fibril aggregation assessed as aggregation level at 100 uM measured on day 10 by UV-visible turbidity method (Rvb = 100 +/- 7.83%) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 20. | ALA4157777 | B | Disaggregation of Cu2+ induced amyloid beta (1 to 40) preformed fibrils assessed as fluorescence emission at 100 uM after 4 days by thioflavin-T based assay (Rvb = 178.07 +/- 17.24 No_unit) | 7 | assay format | Scientific Literature |
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