| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4158679 | B | Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity at 10 uM preincubated for 30 mins followed by tBhQ-mediated Ca2+ depletion and Ca2+ re-addition to extracellular solution measured for 600 secs by Fluo-4 AM-based fluorometric assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 2. | ALA4158682 | B | Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated for 30 mins followed by tBhQ-mediated Ca2+ depletion and Ca2+ re-addition to extracellular solution measured for 600 secs by Fluo-4 AM-based fluorometric assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 3. | ALA4158685 | A | Cytotoxicity against HEK cells assessed as cell viability at 10 uM by MTT assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 4. | ALA4158692 | A | Metabolic stability in CD1 mouse plasma assessed as residual compound level at 50 uM after 30 mins by LC-UV analysis | Mus musculus | 24 | cell-free format | Scientific Literature |
The page will load shortly, Thanks for your patience!