| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4158156 | Functional | Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay | Homo sapiens | 30 | ALA4152367 | cell-based format | Scientific Literature | |
| 2. | ALA4158157 | Functional | Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assay relative to propionate | Homo sapiens | 27 | ALA4152367 | cell-based format | Scientific Literature | |
| 3. | ALA4158158 | Functional | Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRET assay | Homo sapiens | 25 | ALA4152367 | cell-based format | Scientific Literature | |
| 4. | ALA4158159 | Functional | Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRET assay relative to propionate | Homo sapiens | 25 | ALA4152367 | cell-based format | Scientific Literature | |
| 5. | ALA4158163 | Binding | Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometry | Homo sapiens | 6 | ALA4152367 | cell-based format | Scientific Literature | |
| 6. | ALA4158196 | ADME | AUC (0 to infinity) in Balb/c mouse at 5 mg/kg, ip by HPLC-MS/MS analysis | Mus musculus | 2 | ALA4152367 | organism-based format | Scientific Literature | |
| 7. | ALA4158197 | ADME | Half life in Balb/c mouse at 5 mg/kg, ip by HPLC-MS/MS analysis | Mus musculus | 2 | ALA4152367 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!