# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4141033 | Functional | Cytotoxicity against human A2780 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
2. | ALA4141034 | Functional | Cytotoxicity against human Ramos cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
3. | ALA4141035 | Functional | Cytotoxicity against human Jurkat 16 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
4. | ALA4141036 | Functional | Cytotoxicity against human NOMO1 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
5. | ALA4141037 | Functional | Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
6. | ALA4141047 | Functional | Induction of apoptosis in human Jurkat 16 cells assessed as activation of caspase 3 at 1 uM using Ac-DEVD-AMC as substrate measured up to 4 hrs by immuno blot analysis | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
7. | ALA4141048 | Functional | Induction of apoptosis in human Jurkat 16 cells assessed as maximum activation of caspase 3 at 1 uM using Ac-DEVD-AMC as substrate measured after 6 to 7 hrs by immuno blot analysis | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
8. | ALA4141049 | Functional | Induction of apoptosis in human Ramos cells assessed as activation of caspase 3 at 1 uM using Ac-DEVD-AMC as substrate measured up to 4 hrs by immuno blot analysis | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
9. | ALA4141050 | Functional | Induction of apoptosis in human Ramos cells assessed as maximum activation of caspase 3 at 1 uM using Ac-DEVD-AMC as substrate measured after 6 to 7 hrs by immuno blot analysis | Homo sapiens | 3 | ALA4138145 | cell-based format | Scientific Literature | |
10. | ALA4141051 | Functional | Induction of apoptosis in human Jurkat 16 cells assessed as increase in PARP cleavage at 1 uM measured up to 4 to 8 hrs by immuno blot analysis | Homo sapiens | 2 | ALA4138145 | cell-based format | Scientific Literature | |
11. | ALA4141052 | Functional | Induction of apoptosis in human Ramos cells assessed as increase in PARP cleavage at 1 uM measured up to 4 to 8 hrs by immuno blot analysis | Homo sapiens | 2 | ALA4138145 | cell-based format | Scientific Literature | |
12. | ALA4141055 | Functional | Induction of apoptosis in human Ramos cells assessed as PARP cleavage at 1 uM cotreated with pan-caspase inhibitor QVD-OPh measured after 2 to 8 hrs by Western blot analysis | Homo sapiens | 2 | ALA4138145 | cell-based format | Scientific Literature | |
13. | ALA4141057 | Functional | Inhibition of autophagy in mouse MEF expressing mCitrine-hLC3B assessed as reduction in amino acid starvation-induced degradation of LC3 at 10 uM after 4 hrs by flow cytometry | Mus musculus | 3 | ALA4138145 | cell-based format | Scientific Literature | |
14. | ALA4141058 | Functional | Inhibition of autophagy in mouse MEF expressing mCitrine-hLC3B assessed as reduction in amino acid starvation-induced degradation of LC3 at 10 uM cotreated with pan-caspase inhibitor QVD-OPh after 4 hrs by flow cytometry | Mus musculus | 1 | ALA4138145 | cell-based format | Scientific Literature |