| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4153356 | B | Inhibition of GST-tagged human recombinant Aurora A kinase domain (123 to 401 residues) expressed in Sf9 cells after 120 mins by kinase-glo luminescence assay | Homo sapiens | 26 | ALA4152212 | cell-based format | Scientific Literature | |
| 2. | ALA4153357 | B | Inhibition of human recombinant full length Aurora-B (1 to 344 residues) expressed in Sf9 cells after 90 mins by kinase-glo luminescence assay | Homo sapiens | 26 | ALA4152212 | cell-based format | Scientific Literature | |
| 3. | ALA4153358 | B | Inhibition of Aurora-A autophosphorylation at Thr288 in human HCT116 cells after 1 hr by Western blot analysis | Homo sapiens | 5 | ALA4152212 | cell-based format | Scientific Literature | |
| 4. | ALA4153359 | B | Inhibition of Aurora-B autophosphorylation at Thr232 in human HCT116 cells after 1 hr by Western blot analysis | Homo sapiens | 5 | ALA4152212 | cell-based format | Scientific Literature | |
| 5. | ALA4153360 | F | Cytotoxicity against human HCT116 cells | Homo sapiens | 5 | ALA4152212 | cell-based format | Scientific Literature | |
| 6. | ALA4153361 | A | Cytotoxicity against human Detroit 551 cells | Homo sapiens | 5 | ALA4152212 | cell-based format | Scientific Literature | |
| 7. | ALA4153362 | B | Selectivity ratio of IC50 for Aurora-A autophosphorylation at Thr288 in human HCT116 cells to IC50 for Aurora-B autophosphorylation at Thr232 in human HCT116 cells | Homo sapiens | 3 | ALA4152212 | cell-based format | Scientific Literature | |
| 8. | ALA4153364 | F | Increase in mitotic index in human HeLa cells after 10 to 12 hrs post thymidine block by pHH3Ser10/Hoechst33342 staining-based immunofluorescence analysis | Homo sapiens | 2 | ALA4152212 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!