# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4147359 | B | Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylation using [methyl-3H]AdoMet measured after 1 hr | Bacteria | 45 | assay format | Scientific Literature | ||
2. | ALA4147360 | B | Inhibition of recombinant bacterial ErmC' expressed in Escherichia coli DH5alpha assessed as potentiation of erythromycin-mediated growth inhibition by measuring erythromycin MIC after 18 hrs by dilution method (Rvb = > 2560 mg/L) | Bacteria | 45 | assay format | Scientific Literature | ||
3. | ALA4147361 | A | Antibacterial activity against Escherichia coli DH5alpha expressing recombinant bacterial ErmC' after 18 hrs by dilution method | Escherichia coli | 45 | organism-based format | Scientific Literature | ||
4. | ALA4147364 | B | Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-3H]SAM | Bacteria | 1 | assay format | Scientific Literature | ||
5. | ALA4147366 | B | Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli BL21(DE3) assessed as decrease of protein binding to [gamma-33P]ATP-labeled 32-nt oligonucleotide at 5.01 mM after 30 mins by filter binding assay relative to control | Bacteria | 1 | assay format | Scientific Literature | ||
6. | ALA4147372 | A | Cytotoxicity against HEK293 cells assessed as cell viability at 125 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4147373 | A | Cytotoxicity against HEK293 cells assessed as cell viability at 1000 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA5259871 | B | Inhibition of Bacillus subtilis ErmC' methyltransferase | Bacillus subtilis | 7 | single protein format | Scientific Literature |