| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4147114 | F | Inhibition of RANKL/mCSF-induced osteoclast differentiation in C57BL/6 mouse BMMC assessed as reduction in TRAP-positive multinucleated cells at 30 uM by microscopic method relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4147116 | A | Cytotoxicity against C57BL/6 mouse BMMC up to 100 uM after 48 hrs by CCK8 assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4147117 | B | Binding affinity to recombinant human sRANKL expressed in Escherichia coli by SPR assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4147118 | B | Binding affinity to recombinant human sRANKL expressed in Escherichia coli assessed as association constant by SPR assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 5. | ALA4147119 | B | Binding affinity to recombinant human sRANKL expressed in Escherichia coli assessed as dissociation constant by SPR assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 6. | ALA4147121 | A | Drug metabolism assessed as alpha-chymotrypsin (unknown origin)-mediated compound degradation by measuring parent compound remaining after 8 hrs by HPLC analysis | Homo sapiens | 2 | assay format | Scientific Literature |
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