# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4149751 | B | Inhibition of human NaPi2a expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
2. | ALA4149752 | A | Inhibition of human NaPi2b expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
3. | ALA4149753 | B | Inhibition of human NaPi2c expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
4. | ALA4149754 | B | Inhibition of human Pit-1 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
5. | ALA4149755 | B | Inhibition of human Pit-2 expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
6. | ALA4149756 | F | Inhibition of 33P-radiolabeled Pi uptake in human HEK293 cells coexpressing tetracyclin incubated for 20 to 30 mins prior to substrate addition | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature | |
7. | ALA4149757 | P | Lipophilicity, log D of compound by shake-flask method | 12 | ALA4145593 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4149758 | A | Apparent intrinsic clearance in rat liver microsomes | Rattus norvegicus | 12 | ALA4145593 | microsome format | Scientific Literature | |
9. | ALA4149759 | A | Apparent permeability of the compound across apical to basolateral side in RRCK cells | Canis lupus familiaris | 12 | ALA4145593 | cell-based format | Scientific Literature | |
10. | ALA4149760 | P | Apparent aqueous solubility of the compound at pH 6.5 | 12 | ALA4145593 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4149761 | A | Apparent intrinsic clearance in human liver microsomes | Homo sapiens | 2 | ALA4145593 | microsome format | Scientific Literature | |
12. | ALA4149762 | B | Displacement of (C[3H]3) from NaPi2a (unknown origin) expressed in HEK293 cell membranes coexpressing tetracyclin after 1 hr by scintillation counting method | Homo sapiens | 12 | ALA4145593 | cell-based format | Scientific Literature |