# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4133270 | F | Growth inhibition of human MV4-11 cells after 72 hrs by resazurin dye based assay | Homo sapiens | 32 | ALA4130417 | cell-based format | Scientific Literature | |
2. | ALA4133271 | B | Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells assessed as residual activity at 10 uM using N-terminal TAMRA-labeled eIF4E (202 to 214 residues) as substrate by IMAP TR-FRET assay relative to control | Homo sapiens | 32 | ALA4130417 | cell-based format | Scientific Literature | |
3. | ALA4133272 | B | Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system assessed as residual activity at 10 uM using N-terminal TAMRA-labeled eIF4E (202 to 214 residues) as substrate by IMAP TR-FRET assay relative to control | Homo sapiens | 32 | ALA4130417 | assay format | Scientific Literature | |
4. | ALA4133273 | B | Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay | Homo sapiens | 11 | ALA4130417 | single protein format | Scientific Literature | |
5. | ALA4133274 | B | Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 residues) as substrate by IMAP TR-FRET assay | Homo sapiens | 10 | ALA4130417 | cell-based format | Scientific Literature | |
6. | ALA4133275 | B | Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4E (202 to 214 residues) as substrate by IMAP TR-FRET assay | Homo sapiens | 23 | ALA4130417 | assay format | Scientific Literature | |
7. | ALA4133276 | B | Inhibition of recombinant human full length CDK2/Cyclin-A assessed as residual activity at 10 uM using histone H1 as substrate after 40 mins in presence of [gamma33P]-ATP by radiometric method relative to control | Homo sapiens | 23 | ALA4130417 | protein complex format | Scientific Literature | |
8. | ALA4133277 | B | Inhibition of recombinant human full length CDK9/Cyclin-T1 assessed as residual activity at 10 uM using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate after 40 mins in presence of [gamma33P]-ATP by radiometric method relative to control | Homo sapiens | 23 | ALA4130417 | protein complex format | Scientific Literature | |
9. | ALA4133279 | B | ATP competitive inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system assessed as ratio of IC50 in presence of 2 mM ATP to IC50 in presence of 0.05 mM ATP using eIF4E (202 to 214 residues) as substrate by ADP-Glo assay | Homo sapiens | 4 | ALA4130417 | assay format | Scientific Literature | |
10. | ALA4133281 | B | Competitive inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system assessed as ratio of IC50 in presence of 3 mM eIF4E substrate to IC50 in presence of 0.15 mM eIF4E substrate by ADP-Glo assay | Homo sapiens | 4 | ALA4130417 | assay format | Scientific Literature | |
11. | ALA4133284 | B | Inhibition of recombinant human FLT3 assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate by ATP-Glo assay relative to control | Homo sapiens | 2 | ALA4130417 | single protein format | Scientific Literature | |
12. | ALA4133285 | B | Inhibition of FLT1 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | single protein format | Scientific Literature | |
13. | ALA4133286 | B | Inhibition of CDK1/Cyclin-B (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | protein complex format | Scientific Literature | |
14. | ALA4133287 | B | Inhibition of CDK4/Cyclin-D1 (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | protein complex format | Scientific Literature | |
15. | ALA4133288 | B | Inhibition of CDK6/Cyclin-D3 (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | protein complex format | Scientific Literature | |
16. | ALA4133289 | B | Inhibition of CDK7/Cyclin-H (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | protein complex format | Scientific Literature | |
17. | ALA4133290 | B | Inhibition of BRAF (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | single protein format | Scientific Literature | |
18. | ALA4133291 | B | Inhibition of MAPK1 (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | single protein format | Scientific Literature | |
19. | ALA4133292 | B | Inhibition of MAPK2 (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | single protein format | Scientific Literature | |
20. | ALA4133293 | B | Inhibition of PI3K (unknown origin) assessed as residual activity at 10 uM relative to control | Homo sapiens | 2 | ALA4130417 | assay format | Scientific Literature |