| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4137778 | B | Inhibition of human plasma BuChE using acetylthiocholine iodide as substrate by Ellman's method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4137779 | B | Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4137780 | B | Inhibition of recombinant human MAO-A using tyramine as substrate ampliflu red dye based fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4137781 | B | Inhibition of recombinant human MAO-B using tyramine as substrate ampliflu red dye based fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4137782 | B | Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4137783 | B | Displacement of (+)-[3H]pentazocine from human sigma1 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation counting method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4137785 | B | Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 60 mins by liquid scintillation counting method | Rattus norvegicus | 6 | cell membrane format | Scientific Literature | ||
| 8. | ALA4137786 | B | Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cell membranes after 60 mins by liquid scintillation counting method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA4137787 | B | Selectivity ratio of Ki for sigma2 receptor in rat liver membranes to Ki for human sigma1 receptor expressed in HEK293 cell membranes | 2 | cell-based format | Scientific Literature | |||
| 10. | ALA4137788 | F | In vivo agonist activity at sigma1 receptor in sc dosed capsaicin-induced mechanical allodynia CD-1 mouse model assessed as decrease in paw withdrawal latency pretreated for 30 mins followed by capsaicin treatment measured after 2 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4137790 | F | Cognitive enhancing effect in Balb/c mouse assessed as protection against amyloid beta (1 to 42) oligomers-induced memory damage at 1 to 10 mg/kg, po qd via gavage for 17 days starting from 24 hrs post amyloid beta (1 to 42) oligomer treatment measured on day 14 by Y-maze test | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4137792 | A | Induction of memory damage in Balb/c mouse at 1 to 10 mg/kg, po qd via gavage for 17 measured on day 14 by Y-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4137793 | F | Cognitive enhancing effect in amyloid beta (1 to 42)-induced dementia Balb/c mouse model assessed as protection against spatial memory impairment by measuring latency to find food on second, third and fourth days of test at 1 to 10 mg/kg, po qd via gavage for 17 days starting from 24 hrs post amyloid beta (1 to 42) oligomer treatment measured on day 14 by radial arm-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4137796 | F | Cognitive enhancing effect in amyloid beta (1 to 42)-induced dementia Balb/c mouse model assessed as protection against spatial memory impairment by measuring reduction in total errors to find food on second, third and fourth days of test at 1 to 10 mg/kg, po qd via gavage for 17 days starting from 24 hrs post amyloid beta (1 to 42) oligomer treatment measured on day 14 by radial arm-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4329054 | B | Binding affinity to human H3 receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4329055 | B | Inhibition of human MAOA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4329056 | B | Inhibition of human MAOB | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4329057 | B | Inhibition of human AChE | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4329058 | B | Inhibition of human BuChE | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4337198 | B | Inhibition of human histamine H3 receptor | Homo sapiens | 6 | single protein format | Scientific Literature |
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