#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4133148	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake after 25 mins by flow cytometric analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
2.	ALA4133149	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by ATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	8	ALA4130413	single protein format	Scientific Literature
3.	ALA4133151	B	Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins followed by ATP addition measured after 20 mins by spectrofluorometric analysis	Homo sapiens	9	ALA4130413	cell-based format	Scientific Literature
4.	ALA4133152	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced ethidium iodide uptake after 30 mins by spectrofluorometric analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
5.	ALA4133153	B	Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of BzATP-induced current at holding potential of -60 mV preincubated for 5 mins followed by BzATP addition measured after 5 mins by Whole cell patch-clamp analysis	Mus musculus	3	ALA4130413	single protein format	Scientific Literature
6.	ALA4133194	B	Antagonist activity at human P2X7 receptor expressed in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake at 750 nM after 30 mins by FLIPR assay relative to 1 mM ATP	Homo sapiens	1	ALA4130413	assay format	Scientific Literature
7.	ALA4133195	T	Toxicity in Swiss mouse peritoneal macrophages assessed as LDH release at 750 nM after 60 mins relative to 0.05% Triton X-100	Mus musculus	1	ALA4130413	cell-based format	Scientific Literature
8.	ALA4133196	B	Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake at 750 nM preincubated for 10 mins followed by ATP addition measured after 20 mins by FLIPR assay relative to 1 mM ATP	Homo sapiens	1	ALA4130413	cell-based format	Scientific Literature
9.	ALA4252246	B	Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated for 10 mins followed by ATP induction measured after 25 mins by fluorescence assay	Mus musculus	11	ALA4251561	single protein format	Scientific Literature
10.	ALA4252247	A	Cytotoxicity against Swiss Webster mouse peritoneal macrophages by LDH release assay	Mus musculus	5	ALA4251561	cell-based format	Scientific Literature
11.	ALA4252248	T	Selectivity index, ratio of CC50 for Swiss Webster mouse peritoneal macrophages to IC50 for antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages	Mus musculus	5	ALA4251561	assay format	Scientific Literature
12.	ALA4252249	F	Antiinflammatory activity in LPS/IFNgamma-differentiated human THP1 cells assessed as inhibition of ATP-induced IL-1beta release after 30 mins by ELISA	Homo sapiens	5	ALA4251561	cell-based format	Scientific Literature
13.	ALA4252250	F	Antiinflammatory activity in LPS/IFNgamma-differentiated Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced IL-1beta release preincubated for 15 mins followed by ATP/LPS challenge measured after 30 mins by sandwich ELISA	Mus musculus	5	ALA4251561	cell-based format	Scientific Literature
14.	ALA4252251	B	Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins followed by ATP induction measured after 25 mins by fluorescence assay	Homo sapiens	5	ALA4251561	cell-based format	Scientific Literature
15.	ALA4252519	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 after 30 days by thioflavin T staining-based spectrofluorimetric analysis relative to control	Homo sapiens	2	ALA4251568	assay format	Scientific Literature
16.	ALA4252520	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 after 30 days by congo dye-based UV-VIS spectrophotometric analysis	Homo sapiens	2	ALA4251568	assay format	Scientific Literature
17.	ALA4252521	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 after 30 days by thioflavin T staining-based spectrofluorimetric analysis	Homo sapiens	2	ALA4251568	assay format	Scientific Literature
18.	ALA4252522	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 assessed as amorphous aggregates formation after 30 days by TEM analysis	Homo sapiens	1	ALA4251568	assay format	Scientific Literature
19.	ALA4252523	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 assessed as globular aggregates formation after 30 days by TEM analysis	Homo sapiens	1	ALA4251568	assay format	Scientific Literature
20.	ALA4252525	B	Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 assessed as oligomer height after 30 days by AFM analysis (Rvb = 1.9 +/- 1.5 nm)	Homo sapiens	2	ALA4251568	assay format	Scientific Literature