| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4153629 | B | Inhibition of yeast GCN5 (99 to 262 residues) expressed in Escherichia coli BL21 (DE3) at 33 uM preincubated for 15 mins followed by biotin tagged H3 peptide ( 1 to 23 residues) and [3H]-Ac-CoA addition and measured after 60 mins by radioactive acetylation assay | Saccharomyces cerevisiae | 5 | assay format | Scientific Literature | ||
| 2. | ALA4153630 | F | Antiproliferative activity against human MV4-11 cells after 3 days by celltiter-glo luminescent assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4153649 | B | Inhibition of GCN5 in human MV4-11 cells assessed as reduction of acetylated H3K14 level up to 100 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4628753 | A | Cytotoxicity against human SH-SY5Y cells at 100 uM by MTT assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4628754 | B | Selectivity index, ratio of IC50 for equine BuchE using butyrylthiocholine as substrate by Ellman's method to IC50 for human BuchE | 2 | assay format | Scientific Literature | |||
| 6. | ALA4628755 | B | Selectivity index, ratio of IC50 for human AchE to IC50 for human BuchE | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA4628756 | A | Inhibition of human AchE | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4628757 | A | Inhibition of human AchE at 100 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4628758 | B | Inhibition of human BuchE | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 10. | ALA4628759 | B | Selectivity index, ratio of IC50 for electric eel AchE using acetylthiocholine as substrate by Ellman's method to IC50 for equine BuchE using butyrylthiocholine as substrate by Ellman's method | 9 | assay format | Scientific Literature | |||
| 11. | ALA4628760 | A | Inhibition of electric eel AchE using acetylthiocholine as substrate by Ellman's method | Electrophorus electricus | 9 | single protein format | Scientific Literature | ||
| 12. | ALA4628761 | A | Inhibition of electric eel AchE at 100 uM using acetylthiocholine as substrate by Ellman's method relative to control | Electrophorus electricus | 8 | single protein format | Scientific Literature | ||
| 13. | ALA4628762 | B | Inhibition of equine BuchE using butyrylthiocholine as substrate by Ellman's method | Equus caballus | 9 | single protein format | Scientific Literature |
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