# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4145211 | Binding | Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysis | Homo sapiens | 35 | ALA4138313 | cell-based format | Scientific Literature | |
2. | ALA4145212 | ADME | Cytotoxicity against human OVCAR8 cells assessed as cell survival at 10 uM after 4 to 7 days by cell-titer glo assay | Homo sapiens | 4 | ALA4138313 | cell-based format | Scientific Literature | |
3. | ALA4145217 | ADME | Cytotoxicity against mouse wild type MEF cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay | Mus musculus | 24 | ALA4138313 | cell-based format | Scientific Literature | |
4. | ALA4145218 | ADME | Cytotoxicity against mouse PARP1 deficient MEF cells assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay | Mus musculus | 9 | ALA4138313 | cell-based format | Scientific Literature | |
5. | ALA4145220 | ADME | Cytotoxicity against mouse PARP2 deficient MEF cells expressing PARP1 assessed as reduction in cell viability after 4 to 7 days by cell-titer glo assay | Mus musculus | 31 | ALA4138313 | cell-based format | Scientific Literature |