| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4130818 | B | Inhibition of perforin (unknown origin)-mediated 51Cr-labelled human Jurkat cell lysis preincubated with protein for 30 mins followed by cell addition measured after 4 hrs by gamma counting method | Homo sapiens | 71 | cell-based format | Scientific Literature | ||
| 2. | ALA4130819 | B | Inhibition of perforin in human KHYG-1 cells assessed as decrease in lysis of 51Cr-labelled human K562 cells at 10 uM preincubated for 20 mins followed by addition of 51Cr-labelled human K562 cells measured after 4 hrs by gamma counting method relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4130820 | A | Cytotoxicity against human KHYG-1 cells assessed as decrease in cell viability at 10 uM after 24 hrs by trypan blue exclusion assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA4130826 | A | Plasma half life in C57BL/6J mouse at 10 mg/kg, ip by LC-MS/MS method | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA4130827 | A | Cmax in C57BL/6J mouse at 10 mg/kg, ip by LC-MS/MS method | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA4130828 | A | AUC (0 to infinity) in C57BL/6J mouse at 10 mg/kg, ip by LC-MS/MS method | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA5152579 | A | Elimination half life in mouse plasma at 10 to 160 mg/kg, po measured for 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA5152580 | A | Plasma protein binding in mouse | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 9. | ALA5152581 | B | Inhibition of Perforin-1 in human KHYG-1 cells assessed as unbound concentration | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5152583 | T | Toxicity in C57BL/6 mouse assessed as animal survival at 100 mg/kg, po measured for 2 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5152584 | T | Toxicity in C57BL/6 mouse assessed as effect on aspartate transaminase level at 100 mg/kg, po measured for 2 days | Mus musculus | 1 | organism-based format | Scientific Literature |
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