# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4157839 | Binding | Inhibition of LfrA in Mycobacterium smegmatis MC2 155 ATCC 700084 assessed as potentiation of norfloxacin-induced bactericidal activity at 25 ug/ml after 24 to 48 hrs | Mycolicibacterium smegmatis MC2 155 | 2 | ALA4152357 | single protein format | Scientific Literature | |
2. | ALA4157840 | ADME | Growth inhibition of Mycobacterium smegmatis MC2 155 ATCC 700084 after 72 hrs by MTT assay | Mycolicibacterium smegmatis | 18 | ALA4152357 | organism-based format | Scientific Literature | |
3. | ALA4157848 | Binding | Inhibition of LfrA in Mycobacterium smegmatis MC2 155 ATCC 700084 assessed as decrease in norfloxacin MIC at 25 ug/ml after 72 hrs by MTT assay relative to control | Mycolicibacterium smegmatis MC2 155 | 8 | ALA4152357 | single protein format | Scientific Literature | |
4. | ALA4157858 | ADME | Cytotoxicity against rat CC1 cells assessed as decrease in cell survival at 200 ug/ml after 24 hrs by Alamar blue reduction assay relative to control | Rattus norvegicus | 10 | ALA4152357 | cell-based format | Scientific Literature | |
5. | ALA4157859 | ADME | Cytotoxicity against rat CC1 cells assessed as cell survival at 100 ug/ml after 24 hrs by Alamar blue reduction assay relative to control | Rattus norvegicus | 10 | ALA4152357 | cell-based format | Scientific Literature | |
6. | ALA4157860 | ADME | Cytotoxicity against rat CC1 cells assessed as cell survival at 50 ug/ml after 24 hrs by Alamar blue reduction assay relative to control | Rattus norvegicus | 10 | ALA4152357 | cell-based format | Scientific Literature | |
7. | ALA4157865 | Binding | Inhibition of LfrA in Mycobacterium smegmatis MC2 155 ATCC 700084 assessed as increase in norfloxacin accumulation at 25 ug/ml measured every 5 mins for 35 mins by fluorometric analysis | Mycolicibacterium smegmatis MC2 155 | 5 | ALA4152357 | single protein format | Scientific Literature |