# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4143482 | Functional | Antiproliferative activity against human K562 cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature | |
2. | ALA4143483 | Binding | Inhibition human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 37 | ALA4138231 | assay format | Scientific Literature | |
3. | ALA4143484 | Binding | Inhibition human recombinant full length His-tagged Plk1 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 37 | ALA4138231 | assay format | Scientific Literature | |
4. | ALA4143485 | Binding | Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assay | Homo sapiens | 37 | ALA4138231 | assay format | Scientific Literature | |
5. | ALA4143486 | Binding | Selectivity index, ratio of IC50 for human recombinant full length His-tagged Plk1 expressed in baculovirus expression system to IC50 for human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system | Homo sapiens | 37 | ALA4138231 | assay format | Scientific Literature | |
6. | ALA4143487 | Binding | Selectivity index, ratio of IC50 for human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system to IC50 for human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system | Homo sapiens | 37 | ALA4138231 | assay format | Scientific Literature | |
7. | ALA4143488 | Functional | Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature | |
8. | ALA4143489 | Functional | Antiproliferative activity against human HuH7 cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature | |
9. | ALA4143490 | Functional | Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature | |
10. | ALA4143491 | Functional | Antiproliferative activity against human NCI-H1975 cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature | |
11. | ALA4143492 | Functional | Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay | Homo sapiens | 36 | ALA4138231 | cell-based format | Scientific Literature |