# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4158239 | B | Inhibition of recombinant human cytosolic PTPepsilon expressed in Escherichia coli BL21 (DE3) using E527-P-Q-pY530-Q-P-G-E-N-L536 as substrate after 60 mins by malachite green assay | Homo sapiens | 5 | ALA4152370 | assay format | Scientific Literature | |
2. | ALA4158240 | B | Inhibition of cytosolic PTPepsilon in human monocyte-derived osteoclasts assessed as relative level of Tyr530 phosphorylated c-Src/beta actin at 17 uM after 15 mins in presence of M-CSF/RANKL by Western blot method relative to control | Homo sapiens | 2 | ALA4152370 | single protein format | Scientific Literature | |
3. | ALA4158241 | A | Effect on relative level of total c-Src/beta-actin in human monocyte-derived osteoclasts at 17 uM after 15 mins in presence of M-CSF/RANKL by Western blot method relative to control | Homo sapiens | 2 | ALA4152370 | cell-based format | Scientific Literature | |
4. | ALA4158242 | B | Inhibition of cytosolic PTPepsilon in human monocyte-derived osteoclasts assessed as disruption of podosome organization at 17 uM after 4 days in presence of M-CSF/RANKL by DAPI staining-based immunofluorescence assay | Homo sapiens | 2 | ALA4152370 | single protein format | Scientific Literature | |
5. | ALA4158243 | F | Inhibition of RANKL-induced human monocytes differentiation into osteoclasts after 4 days in presence of M-CSF by tartrate-resistant acid phosphatase staining based assay | Homo sapiens | 2 | ALA4152370 | cell-based format | Scientific Literature | |
6. | ALA4158244 | A | Cytotoxicity against human monocyte-derived osteoclasts assessed as effect on cell viability at 2 to 17 uM by formazan-based spectrometric method | Homo sapiens | 2 | ALA4152370 | cell-based format | Scientific Literature |