| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4145311 | B | Displacement of [3H]-diprenorphine from human DOR expressed in CHO cell membranes after 80 mins by scintillation counting analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4145312 | B | Displacement of [3H]-diprenorphine from human MOR expressed in CHO cell membranes after 80 mins by scintillation counting analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA4145313 | B | Displacement of [3H]-diprenorphine from human mu-delta opioid receptor heterodimer expressed in CHO cell membranes at high site fraction after 80 mins by scintillation counting analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA4145314 | B | Displacement of [3H]-diprenorphine from human mu-delta opioid receptor expressed in CHO cell membranes after 80 mins by scintillation counting analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA4145316 | B | Selectivity ratio of KiH for human mu-delta opioid receptor heterodimer expressed in CHO cell membranes to Ki for human DOR expressed in CHO cell membranes | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA4145317 | F | Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding at high site fraction preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA4145318 | F | Antagonist activity at human mu-delta opioid receptor heterodimer expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding at high site fraction preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4145319 | F | Antagonist activity at human DOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4145320 | F | Antagonist activity at human MOR expressed in CHO cell membranes assessed as inhibition of CYM51010-induced [35S]-GTPgammaS binding preincubated for 5 mins followed by CYM51010 and [35S]-GTPgammaS addition measured after 80 mins | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4145321 | B | Selectivity ratio of IC50H for human mu-delta opioid receptor heterodimer expressed in CHO cell membranes to IC50 for human DOR expressed in CHO cell membranes | Homo sapiens | 6 | cell-based format | Scientific Literature |
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