| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4151511 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux at 50 uM incubated for 5 mins by fluorescence based assay | Staphylococcus aureus | 44 | ALA4145675 | single protein format | Scientific Literature | |
| 2. | ALA4151512 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluorescence based assay | Staphylococcus aureus | 44 | ALA4145675 | single protein format | Scientific Literature | |
| 3. | ALA4151513 | A | Antimicrobial activity against Staphylococcus aureus SA-1199B expressing wild type norA and co-expressing GrlA A116E mutant by microdilution method | Staphylococcus aureus | 44 | ALA4145675 | organism-based format | Scientific Literature | |
| 4. | ALA4151514 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as minimal potentiating drug concentration causing 8 fold reduction in ciprofloxacin MIC by microdilution method based Checkerboard assay | Staphylococcus aureus | 44 | ALA4145675 | single protein format | Scientific Literature | |
| 5. | ALA4151515 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against wild type Staphylococcus aureus ATCC 25923 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | ALA4145675 | organism-based format | Scientific Literature | |
| 6. | ALA4151516 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against Staphylococcus aureus SA-1199 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | ALA4145675 | organism-based format | Scientific Literature | |
| 7. | ALA4151517 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 21 | ALA4145675 | single protein format | Scientific Literature | |
| 8. | ALA4151518 | B | Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 7 | ALA4145675 | single protein format | Scientific Literature | |
| 9. | ALA4151520 | B | Inhibition of NorA in Staphylococcus aureus SA-K2378 assessed as synergistic potentiation of ciprofloxacin-induced antimicrobial activity at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 7 | ALA4145675 | single protein format | Scientific Literature | |
| 10. | ALA4151521 | F | Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against norA deleted Staphylococcus aureus SA-K1902 at 0.78 to 100 ug/ml by microdilution method based Checkerboard assay | Staphylococcus aureus | 7 | ALA4145675 | organism-based format | Scientific Literature | |
| 11. | ALA4151523 | A | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay | Homo sapiens | 25 | ALA4145675 | cell-based format | Scientific Literature | |
| 12. | ALA4151524 | A | Cytotoxicity in human THP1 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay | Homo sapiens | 25 | ALA4145675 | cell-based format | Scientific Literature | |
| 13. | ALA4151525 | A | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 14. | ALA4151528 | A | Antimicrobial activity against Staphylococcus aureus SA-1199B expressing wild type norA by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 15. | ALA4151529 | A | Antimicrobial activity against NorA deficient Staphylococcus aureus SA-K1902 by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 16. | ALA4151530 | A | Antimicrobial activity against NorA overexpressing Staphylococcus aureus SA-K2378 by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 17. | ALA4151531 | A | Antimicrobial activity against mepA deficient Staphylococcus aureus SA-K2885 by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 18. | ALA4151532 | A | Antimicrobial activity against mepA overexpressing Staphylococcus aureus SA-K2886 by microdilution method | Staphylococcus aureus | 25 | ALA4145675 | organism-based format | Scientific Literature | |
| 19. | ALA5135900 | T | Cytotoxicity against HEL 299 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay | Homo sapiens | 14 | ALA5131518 | cell-based format | Scientific Literature | |
| 20. | ALA5135901 | F | Antiviral activity against SARS-CoV-2 infected in eGFP expressing African green monkey Vero E6 cells assessed as reduction in virus-induced cytopathic effect measured after 4 days post infection by laser scanning microscopic analysis | Severe acute respiratory syndrome coronavirus 2 | 42 | ALA5131518 | organism-based format | Scientific Literature |
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