# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4151994 | B | Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes pre-incubated for 1 hr by FRET-based binding assay | Homo sapiens | 47 | ALA4145692 | cell-based format | Scientific Literature | |
2. | ALA4151997 | P | Kinetic solubility in pH 7.4 HEPES-BSA buffer at 5 uM incubated for 24 hrs at 20 degC by HPLC method | 57 | ALA4145692 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4152006 | F | Inhibition of macrophages infiltration in Balb/c mouse model of 8 day model of of allergic eosinophilic airway inflammation at 300 nmol/kg dosed intranasally 2 hrs before ovalbumin challenge by hemocytometry | Mus musculus | 7 | ALA4145692 | organism-based format | Scientific Literature | |
4. | ALA4152007 | F | Inhibition of lymphocytes infiltration in Balb/c mouse model of 8 day model of of allergic eosinophilic airway inflammation at 300 nmol/kg dosed intranasally 2 hrs before ovalbumin challenge by hemocytometry | Mus musculus | 8 | ALA4145692 | organism-based format | Scientific Literature |