| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4152680 | B | Displacement of [3H]CCPA from recombinant human adenosine A1 receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA4152681 | B | Displacement of [3H]NECA from recombinant human adenosine A2A receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA4152682 | F | Antagonist activity at recombinant human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activity after 20 mins by [alpha-32P]ATP assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA4152683 | B | Displacement of [3H]NECA from recombinant human adenosine A3 receptor transfected in CHO cell membranes after 3 hrs by microbeta scintillation counting analysis | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 5. | ALA4152684 | B | Selectivity index, ratio of Ki for recombinant human adenosine A2A receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 6. | ALA4152685 | B | Selectivity index, ratio of Ki for recombinant human adenosine A2B receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 7. | ALA4152686 | B | Selectivity index, ratio of Ki for recombinant human adenosine A3 receptor to Ki for recombinant human adenosine A1 receptor | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 8. | ALA4152687 | F | Antagonist activity at recombinant human adenosine A1 receptor transfected in CHO cells assessed as inhibition of CCPA-induced cAMP accumulation preincubated for 10 mins followed by CCPA addition by GloSensor cAMP assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA4152688 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 20%) | Mus musculus | 1 | assay format | Scientific Literature | ||
| 10. | ALA4152689 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of 0.1 uM CCPA-induced reduction in rhythmic spontaneous contractions by measuring tissue response at 1 uM after 1 hr (Rvb = 65%) | Mus musculus | 1 | assay format | Scientific Literature | ||
| 11. | ALA4152690 | F | Antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 6 | assay format | Scientific Literature | ||
| 12. | ALA4152691 | F | Reversible antagonist activity at adenosine A1 receptor in BALB/C mouse ileum assessed as reversal of CCPA-induced reduction in rhythmic spontaneous contractions at 1 uM incubated for 1 hr measured after compound wash out | Mus musculus | 1 | assay format | Scientific Literature | ||
| 13. | ALA4152692 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on amplitude of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | assay format | Scientific Literature | ||
| 14. | ALA4152693 | F | Activity at adenosine A1 receptor in BALB/C mouse ileum assessed as effect on frequency of rhythmic spontaneous contractions at 1 uM after 1 hr | Mus musculus | 5 | assay format | Scientific Literature |
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