# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146929 | Functional | Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay | Homo sapiens | 38 | ALA4145476 | cell-based format | Scientific Literature | |
2. | ALA4146930 | Functional | Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels at 10'-5 M using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay relative to NMU-8 | Homo sapiens | 37 | ALA4145476 | cell-based format | Scientific Literature | |
3. | ALA4146931 | Functional | Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay | Homo sapiens | 41 | ALA4145476 | cell-based format | Scientific Literature | |
4. | ALA4146932 | Functional | Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels at 10'-5 M using myo-[2-3H(N)]-inositol after 60 mins by SPA-based topcount assay relative to NMU-8 | Homo sapiens | 40 | ALA4145476 | cell-based format | Scientific Literature | |
5. | ALA4146935 | Binding | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | Homo sapiens | 42 | ALA4145476 | cell-based format | Scientific Literature | |
6. | ALA4146936 | Binding | Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | Homo sapiens | 42 | ALA4145476 | cell-based format | Scientific Literature | |
7. | ALA4146937 | Binding | Selectivity ratio of IC50 for human NMUR2 expressed in HEK293 cell membranes to IC50 for NMUR1 expressed in HEK293 cell membranes | Homo sapiens | 36 | ALA4145476 | cell-based format | Scientific Literature |