# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4147209 | Functional | Antiviral activity against wild type HIV1 3B infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 26 | ALA4145492 | organism-based format | Scientific Literature | |
2. | ALA4147210 | Functional | Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 2 | 22 | ALA4145492 | organism-based format | Scientific Literature | |
3. | ALA4147211 | ADME | Cytotoxicity against human MT4 cells assessed as reduction in cell viability after 4 days by MTT assay | Homo sapiens | 26 | ALA4145492 | cell-based format | Scientific Literature | |
4. | ALA4147212 | Toxicity | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for wild type HIV1 3B | 26 | ALA4145492 | assay format | Scientific Literature | ||
5. | ALA4147213 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase L100I mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
6. | ALA4147214 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase K103N mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
7. | ALA4147215 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase Y181C mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
8. | ALA4147216 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase Y188L mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
9. | ALA4147217 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase E138K mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
10. | ALA4147218 | Functional | Antiviral activity against HIV1 RES056 harboring reverse transcriptase K103 N/Y181C double mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
11. | ALA4147219 | Functional | Antiviral activity against HIV1 harboring reverse transcriptase F227L/V106A double mutant infected in human MT4 cells assessed as reduction of virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 8 | ALA4145492 | organism-based format | Scientific Literature | |
12. | ALA4147220 | Binding | Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of biotin-dUTP incorporation after 40 mins by Pico-Green staining based fluorescence assay | Human immunodeficiency virus 1 | 24 | ALA4145492 | single protein format | Scientific Literature |